6LWCA

Crystal structure of human neil1(p2g, e3q, k242) bound to duplex dna containing spiroiminodihydantoin (sp)
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
289
structure length
265
Chain Sequence
GQGPELHLASQFVNEACRALVFGGCVEKSSVSRNPEVPFESSAYRISASARGKELRLILSPLPGAQPQQEPLALVFRFGMSGSFQLVPREELPRHAHLRFYTAPPGPRLALCFVDIRRFGRWDLGGKWQPGRGPCVLQEYQQFRENVLRNLADKAFDRPICEALLDQRFFNGIGNYLRAEILYRLKIPPFEKARSVLEALQNPDLLELCHSVPKEVVQLGGKGYEEDFAAFRAWLRCYGMPGMSSLQDRHGRTIWFQGDPGPLAP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title DNA repair glycosylase hNEIL1 triages damaged bases via competing interaction modes.
rcsb
molecule tags Dna binding protein/dna
source organism Homo sapiens
molecule keywords Endonuclease 8-like 1
total genus 75
structure length 265
sequence length 289
chains with identical sequence D
ec nomenclature ec 4.2.99.18: DNA-(apurinic or apyrimidinic site) lyase.
pdb deposition date 2020-02-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01149 Fapy_DNA_glyco Formamidopyrimidine-DNA glycosylase N-terminal domain
A PF09292 Neil1-DNA_bind Endonuclease VIII-like 1, DNA bind
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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