6MUGG

Crystal structure of hiv-1 b41 sosip.664 prefusion env trimer bound to small molecule hiv-1 entry inhibitor bms-386150 in complex with human antibodies 3h109l and 35o22 at 3.8 angstrom
Total Genus 78
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
78
sequence length
479
structure length
424
Chain Sequence
AKKWVTVYYGVPVWKEATTTLFCASDAEVHNVWATHACVPTDPNPQEIVLGNVTENFNMWKNNMVEQMHEDIISLWDQSLKPCVKLTPLCVTLNCNNVNEMKNCSFNVTTSIRDKIKKEYALFYKLDVVPLTNYRLINCNTSVITQACPKVSFEPIPIHYCAPAGFAILKCNSKTFNGSGPCTNVSTVQCTHGIRPVVSTQLLLNGSLAEEEIVIRSENITDNAKTIIVQLNEAVEINCTRPNNNTRKSIHIGPGRAFYATGDIIGNIRQAHCNISKARWNETLGQIVAKLEEQFPKTIIFNHSSDPEIVTHSFNCGGEFFYCNTTPLFNSTWNNEQNITLQCRIKQIINMWQGVGKAMYAPPIRGQIRCSSNITGLLLTRDNGTETFRPGGGNMRDNWRSELYKYKVVKIEPLGIAPTACKRR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Immune system/inhibitor
molecule keywords Envelope glycoprotein gp160
publication title Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry.
pubmed doi rcsb
source organism Human immunodeficiency virus 1
total genus 78
structure length 424
sequence length 479
ec nomenclature
pdb deposition date 2018-10-23
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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