6MZLA

Human tfiid canonical state
Total Genus 107
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
107
sequence length
1048
structure length
472
Chain Sequence
FSLAGFLFGNINGAGQLEGESVLDDECKKHLAGLGALGLGSLITELTNDEGWVRSTEDAVDYSDINEVAEDIIQHSIPAVELRQPFFPTHMGPIKLRQFHRPPLKKYSFGALSQPGPHSVQPLLKHIKKKAKMREQERQASGGGEMFFMRTPQDLTGKDGDLILAEYSEENGPLMMQVGMATKIKNYYKRKPGKDPGAPDCKYGETVYCHTSPFLGSLHPGQLLQAFENNLFRAPIYLHKMPETDFLIIRTRQGYYIRELVDIFVVGQQCPLFEVPGPNSKRANTHIRDFLQVFIYRLFWKSKDRPRRIRMEDIKKAFPSHSESSIRKRLKLCADFKRTGMDSNWWVLKSDFRLPTEEEIRAMVSPEQCCAYYSMIAAEQRLKDAGYGEKSFKIDDEVRTAPWNTTRAFIAAMKGKCLLEVTGVADPTGCGEGFSYVKIPNKSVAEHQERYKEECQRIFDLQNKVLSSTEVL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transcription
molecule keywords Transcription initiation factor TFIID subunit 1
publication title Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
pubmed doi rcsb
source organism Homo sapiens
total genus 107
structure length 472
sequence length 1048
ec nomenclature ec 2.3.1.48: Histone acetyltransferase.
pdb deposition date 2018-11-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00439 Bromodomain Bromodomain
A PF09247 TBP-binding TATA box-binding protein binding
A PF12157 DUF3591 Protein of unknown function (DUF3591)
A PF15288 zf-CCHC_6 Zinc knuckle
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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