6NZDA

Cryo-em structure of the lysosomal folliculin complex (flcn-fnip2-raga-ragc-ragulator)
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
109
structure length
81
Chain Sequence
TDEQALLSSILAKTASNIIDVSSLTHWKKLPPLPSLTSQPHQVLASEPIPFSDLQQVSRIAAYAYSALSQIRVDAKEELVV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein/inhibitor
molecule keywords Ragulator complex protein LAMTOR1
publication title Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex
doi rcsb
source organism Homo sapiens
total genus 19
structure length 81
sequence length 109
ec nomenclature
pdb deposition date 2019-02-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF15454 LAMTOR Late endosomal/lysosomal adaptor and MAPK and MTOR activator
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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