6O16A

Crystal structure of murine dhx37 in complex with rna
Total Genus 237
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
237
sequence length
919
structure length
798
Chain Sequence
VFIPVNRTPEMQEERLKLPILAEEQAIMEAVAEHPIVIVCGETGSGKTTQVPQFLYEAGYSSEDSIIGVTEPRRVAAVAMSQRVAKEMNLSHRVVSYQIRYEGNVTEETRIKFMTDGVLLKEIQKDFLLLKYKVVIIDEAHERSVYTDILLGLLSRIVALRAKRHLPLKLLIMSATLRVEDFTQNQRLFTTPPPVIKVESRFPVTVHFNDDYSGECFRKVCKIHRMLPAGGILVFLTGQAEVHALCRRLRKAFLPLHVLPLYSLLAPEKQAQVFKPPPGTRLCVVATNVAETSLTIPGIKYVVDCGKVKKRYYDRVTGVSSFRVTWVSQASADQRAGRAGRTEPGHCYRLYSSAVFGDFEQFPPPEITRRPVEDLILQMKALSIEKVINFPFPTPPSVEALVAAEELLVALGALQAQLSCPITALGRTMSTFPVAPRYAKMLALSQQHGCLPYTIAIVAAMTVRELFEELDREKELAELKGRRARVAQMKRTWAGQGPSLKLGDLMVLLGAVGACEYAGCSPQFCQANGLRYKAMLEIRRLRGQLTTAVNAVCPEDPKMQPPTESQVTYLRQIMAAGLGDHLARRVQSLDPKWKNAYKTPLLDDPVFIHPSSVLFKELPEFVVYQEIVETTKMYMKGVSTVEIQWIPSLLPSYCQFDAPLEEPAPSYCPESGQVLCHRASVFYRVGWPLPAVQVDFPEGIDRYKYFAKFLLEGQVFRKLASFKSCLLSSPSTMLKTWARLQPRTETLLRALVAHKADSRDSLLAAWKKNPKYLLAEYCEWLPKAMHSDVEKNWPPTTD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase/rna
molecule keywords DEAH (Asp-Glu-Ala-His) box polypeptide 37
publication title Molecular mechanism of the RNA helicase DHX37 and its activation by UTP14A in ribosome biogenesis.
pubmed doi rcsb
source organism Mus musculus
total genus 237
structure length 798
sequence length 919
chains with identical sequence B
ec nomenclature
pdb deposition date 2019-02-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00270 DEAD DEAD/DEAH box helicase
A PF00271 Helicase_C Helicase conserved C-terminal domain
A PF04408 HA2 Helicase associated domain (HA2)
A PF07717 OB_NTP_bind Oligonucleotide/oligosaccharide-binding (OB)-fold
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the pdb database (?% sequence similarity)

 
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