6P9AA

Hiv-1 protease multiple mutant prs5b with darunavir
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
99
structure length
99
Chain Sequence
PQITLWKRPIITIKIGGQLKDVLMDTGADDTVLENIDLPGKWKPKLIGGIGGFVKVRQYDHVPVEVAGHKVTTTVLVGPTPVDVIGRNLLTQIGATLNF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase/hydrolase inhibitor, viral protein
molecule keywords HIV-1 Protease
publication title Highly drug-resistant HIV-1 protease reveals decreased intra-subunit interactions due to clusters of mutations.
pubmed doi rcsb
source organism Human immunodeficiency virus type 1 group m subtype b (isolate bru/lai)
total genus 15
structure length 99
sequence length 99
chains with identical sequence B
ec nomenclature
pdb deposition date 2019-06-10
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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