6RYUV

Nucleosome-chd4 complex structure (two chd4 copies)
Total Genus 127
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
127
sequence length
767
structure length
708
Chain Sequence
DHHMEFCRVCKDGGELLCCDTCPSSYHIHCLNPPLPEIPNGEWLCPRCTCPALKGKVQKILIWKWGPERQFFVKWQGMSYWHCSWVSELQLELHCQVMFRNYQRKNDMDEPPSEEKSRKRKNKDPKFAEMEERFYRYGIKPEWMMIHRILNHSVDKKGHVHYLIKWRDLPYDQASWESEDVEIQDYDLFKQSYWNHRELMTVDPTVKYERQPEYLDATGGTLHPYQMEGLNWLRFSWAQGTDTILADEMGLGKTVQTAVFLYSLYKEGHSKGPFLVSAPLSTIINWEREFEMWAPDMYVVTYVGDKDSRAIIRENEFSFEDNAIRGGKKASRMKKEASVKFHVLLTSYELITIDMAILGSIDWACLIVDEAHRLKNNQSKFFRVLNGYSLQHKLLLTGTPLQNNLEELFHLLNFLTPERFHNLEGFLEEFADIAKEDQIKKLHDMLGPHMLRRLKADVFKNMPSKTELIVRVELSPMQKKYYKYILTRNFEALNARGGGNQVSLLNVVMDLKKCCNHPYLFPVAAMEAPKMPNGMYDGSALIRASGKLLLLQKMLKNLKEGGHRVLIFSQMTKMLDLLEDFLEHEGYKYERIDGGITGNMRQEAIDRFNAPGAQQFCFLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVEERITQVAKKKMMLTHLVVRXXXXXXXXXXXX
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Transcription
molecule keywords Histone H3.2
publication title Nucleosome-CHD4 chromatin remodeller structure maps human disease mutations.
pubmed doi rcsb
source organism Xenopus laevis
total genus 127
structure length 708
sequence length 767
chains with identical sequence W
ec nomenclature ec 3.6.4.12: DNA helicase.
pdb deposition date 2019-06-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
V PF00176 SNF2_N SNF2 family N-terminal domain
V PF00271 Helicase_C Helicase conserved C-terminal domain
V PF00385 Chromo Chromo (CHRromatin Organisation MOdifier) domain
V PF00628 PHD PHD-finger
V PF06461 DUF1086 Domain of Unknown Function (DUF1086)
V PF06465 DUF1087 Domain of Unknown Function (DUF1087)
V PF08073 CHDNT CHDNT (NUC034) domain
V PF08074 CHDCT2 CHDCT2 (NUC038) domain
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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