6UK1A

Crystal structure of nucleotide-binding domain 2 (nbd2) of the human cystic fibrosis transmembrane conductance regulator (cftr)
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
229
structure length
229
Chain Sequence
DIWPSGGQMTVKDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLLLAFLRLLNTEGEIQIDGVSWDSITLEQWRKAFGVIPQDVFIFSGTFRKNLDPNEQWSDQEIWKVADEVGLRSVIEQFPGGLDFVLVDGGCVLSHGHKQLMCLARAVLSKAKILLLDEPSAHLDPVTYQIIRRTLKQAFADCTVILCEARIEAMLECDQFLVIEENKVRQYDSIQKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase
molecule keywords Cystic fibrosis transmembrane conductance regulator
publication title A thermodynamically stabilized form of the second nucleotide binding domain from human CFTR shows a catalytically inactive conformation
rcsb
source organism Homo sapiens
total genus 61
structure length 229
sequence length 229
chains with identical sequence B, C, D
ec nomenclature ec 5.6.1.6: Channel-conductance-controlling ATPase.
pdb deposition date 2019-10-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00005 ABC_tran ABC transporter
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the pdb database (?% sequence similarity)

 
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