6UU2AAA

E. coli sigma-s transcription initiation complex with 3-nt rna ("old" crystal soaked with gtp and atp for 30 minutes)
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
230
structure length
230
Chain Sequence
TEFLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNLKGLAVRVQGKDEVILTLNKSGIGPVTAADITHDGDVEIVKPQHVICHLTDENASISMRIKVQRGRGYVPASTRIHSEEDERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETNGTIDPEEAIRRAATILAEQLEAFVDLR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Transcription, transferase/dna/rna
molecule keywords DNA-directed RNA polymerase subunit alpha
publication title Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.
pubmed doi rcsb
source organism Escherichia coli
total genus 42
structure length 230
sequence length 230
chains with identical sequence BBB
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2019-10-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
AAA PF01000 RNA_pol_A_bac RNA polymerase Rpb3/RpoA insert domain
AAA PF01193 RNA_pol_L RNA polymerase Rpb3/Rpb11 dimerisation domain
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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