6UX2A

Crystal structure of zikv rdrp in complex with stat2
Total Genus 177
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
177
sequence length
681
structure length
619
Chain Sequence
SLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLFFHFLDQLNQDPESLLLQHNLRKFCRDIQPFSQDPTQLAEMIFNLLPVESQQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRYKIQAKGKTPTKEQKILQETLNELDKRRKEVLDASKALLGRLTTLIELLLPKLEEWKAQQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVQDDPLTKGVDLRNAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQEGNESLTVEVSIDRNPPQQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSGPLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLWFNLLSPNLQNQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRTEDPLLSWADFTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLKKTMSGTFLLRFSESSEGGITCSWVEHQDDDKVLIYSVQPYTKEVLQSLPLTEIIRHYQLLPENPLRFLYPRIPRDEAFGCYYQEKYLKHRLIVVSNRQVDE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Dna binding protein/viral protein
molecule keywords Signal transducer and activator of transcription 2
publication title Structural basis for STAT2 suppression by flavivirus NS5
rcsb
source organism Homo sapiens
total genus 177
structure length 619
sequence length 681
ec nomenclature
pdb deposition date 2019-11-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
A PF01017 STAT_alpha STAT protein, all-alpha domain
A PF02864 STAT_bind STAT protein, DNA binding domain
A PF02865 STAT_int STAT protein, protein interaction domain
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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