6W56A

Trypanosoma cruzi malic enzyme in complex with inhibitor (mec062)
Total Genus 203
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
203
sequence length
544
structure length
544
Chain Sequence
AILTDRYINRGTAFTMEERQKLHILGRLPPVVETLEEQVARVYGQVKKYEKPINRYQHLVSVHSTNTTLYYATILAHLEEMLPIIYTPTVGEACMEYSHLFFRERGVYFNRLYKGQFRNIMRDAGYQKVEVVVITDGSRILGLGDLGSNGIGISIGKCSLYVAGAGIDPRLIVPVILDVGTNNERYLQDKDYLGMREKRLGDEEFYELLDEFMEAASAEWPNAVIQFEDFSNNHCFDIMERYQKKYRCFNDDIQGTGAVIAAGFLNAIKLSGVSPLQQRIVVFGAGSAAVGVANNIAALAARMYKFPVQDLVKTFYLVDTKGLVTTTRGDQLAAHKKLLARTDVSAEDSAKLRTLEEIVRFVKPTTLLGLGGVGPAFTEEIVKMVMQNTERPIIFPLSNPTSKAEVTPENAYKWTNGAAIVASGSPFPPTTIGGKTFKPSQGNNLYVFPGVGLGCALAQPTHIPEELLLTASESLNLLTTEGDLREGRLYPPLEDIHNISANVATDVILEAQRMKIDNNKKLPRTRDELLAFVKKAMWKPVYSG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Oxidoreductase/inhibitor
molecule keywords Malic enzyme
publication title Trypanosoma cruzi Malic Enzyme in complex with inhibitors
rcsb
source organism Trypanosoma cruzi
total genus 203
structure length 544
sequence length 544
ec nomenclature
pdb deposition date 2020-03-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03949 Malic_M Malic enzyme, NAD binding domain
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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