6W89B

Structure of dnmt3a (r882h) in complex with cga dna
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
203
structure length
194
Chain Sequence
MFETVPVWRRQPVRVLSLFEDIKKELTSLGFLESGSQLKHVVDVTDTVRKDVEEWGPFDLVYGATPPLGHTCDRPPSWYLFQFHRLLQYARPKPGSPRPFFWMFVDNLVLNKEDLDVASRFLEMEPVTIPDVHLQNAVRVWSNIPAIRSRHWALVSEEELSLLAQNKQSSKKWPTKLVKNCFLPLREYFKYFST
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/dna
molecule keywords DNA (cytosine-5)-methyltransferase 3A
publication title Structural basis for impairment of DNA methylation by the DNMT3A R882H mutation
rcsb
source organism Homo sapiens
total genus 45
structure length 194
sequence length 203
chains with identical sequence C, H, I
ec nomenclature
pdb deposition date 2020-03-20
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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