6WGG4

Atomic model of pre-insertion mutant occm-dna complex(orc-cdc6-cdt1-mcm2-7 with mcm6 whd truncation)
Total Genus 119
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
119
sequence length
750
structure length
665
Chain Sequence
LRIIWGTNVSIQECTTNFRNFLMSFKYKFRKILDERDEELYYIKQLNEMRELGTSNLNLDARNLLAYKQTEDLYHQLLNYPQEVISIMDQTIKDCMVSLIVDNNLDYDLDEIETKFYKVRPYNVGSCKGMRELNPNDIDKLINLKGLVLRSTPVIPDMKVAFFKCNVCDHTMAVEIDRGVIQEPARCERIDCNEPNSMSLIHNRCSFADKQVIKLQETPDFVPDGQTPHSISLCVYDELVDSCRAGDRIEVTGTFRSKTYVDVVHVKKVSHNEVEEVRQITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGILLQLFGGTNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAYITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASANPIGSYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNLYLEDKPEHISQDDVLPVEFLTMYISYAKEHIHPIITEAAKTELVRAYVGMRKTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKRKLQEDLSREIMNVLKDQASDSMSFNELIKQINEHSQDRVESSDIQEALSRLQQEDKVIVLGEGVRRS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Replication/dna
molecule keywords Cell division cycle protein CDT1
publication title Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6.
pubmed doi rcsb
source organism Saccharomyces cerevisiae
total genus 119
structure length 665
sequence length 750
ec nomenclature ec 3.6.4.12: DNA helicase.
pdb deposition date 2020-04-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
4 PF00493 MCM MCM P-loop domain
4 PF14551 MCM_N MCM N-terminal domain
4 PF17207 MCM_OB MCM OB domain
4 PF17855 MCM_lid MCM AAA-lid domain
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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