6WIHD

N-terminal mutation of iscu2 (l35h36) traps nfs1 cys loop in the active site of iscu2 without metal present. structure of human mitochondrial complex nfs1-iscu2(l35h36)-isd11 with e.coli acp1 at 1.9 a resolution (niau)2.
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
125
structure length
125
Chain Sequence
ALHTQVVDHYENPRNVGSLDKTSKNVGTGLVGAPACGDVMKLQIQVDEKGKIVDARFKTFGCGSAIASSSLATEWVKGKTVEEALTIKNTDIAKELCLPPVKLHCSMLAEDAIKAALADYKLKQE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The essential function of ISCU2 and its conserved N-terminus in Fe/S cluster biogenesis
rcsb
source organism Homo sapiens
molecule tags Transferase
molecule keywords Cysteine desulfurase, mitochondrial
total genus 45
structure length 125
sequence length 125
ec nomenclature
pdb deposition date 2020-04-09
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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