6WO5G

Structure of hepatitis c virus envelope glycoprotein e2 core from genotype 1a bound to neutralizing antibody 212.1.1 and non neutralizing antibody e1
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
226
structure length
220
Chain Sequence
QVQLVQSGAEVKKPGSSVKVSCKASGGTLSSYGISWVRQAPGQGLEWLGGSIPILGTSVYAQKFQGRVTMTADESTSTAHMELSSLRFDDTAIYYCAGVREGMAAISGKNAFDIWGQGTMVTVSSASTKGPSVFPLAPSGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Immune system/viral protein
molecule keywords Fab E1 heavy chain
publication title An alternate conformation of HCV E2 neutralizing face as an additional vaccine target.
pubmed doi rcsb
source organism Homo sapiens
total genus 39
structure length 220
sequence length 226
chains with identical sequence H
ec nomenclature
pdb deposition date 2020-04-24
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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