6X7AAAA

Crystal structure of acetyltransferase eis from mycobacterium tuberculosis in complex with inhibitor sgt572
Total Genus 111
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
111
sequence length
399
structure length
392
Chain Sequence
TLCSPTEDDWPGMFLLAAASFTDFIGPESATAWRTLVPTDGAVVVRDSEVVGMALYMDLRLTVPGEVVLPTAGLSFVAVAPTHRRRGLLRAMCAELHRRIADSGYPVAALHASEGGIYGRFGYGPATTLHELTVDRRFARFHADAPGGGGSSVRLVRPTEHRGEFEAIYERWRQQVPGGLLRPQVLWDELLAEAKAAPGGDRESFALLHPDGYALYRVDRTDLKLARVSELRAVTADAHCALWRALIGLDSMERISIITHPQDPLPHLLTDTRLARTTWRQDGLWLRIMNVPAALEARGYAHEVGEFSTVLEVSDGGRFALKIGDGRARCTPTDAAAEIEMDRDVLGSLYLGAHRASTLAAANRLRTKDSQLLRRLDAAFASDVPVQTAFEF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
molecule keywords N-acetyltransferase Eis
publication title Discovery of Haloperidol and Droperidol as inhibitors of acetyltransferase Eis from Mycobacterium tuberculosis
rcsb
source organism Mycobacterium tuberculosis (strain atcc 25618 / h37rv)
total genus 111
structure length 392
sequence length 399
ec nomenclature ec 2.3.1.-:
pdb deposition date 2020-05-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
AAA PF13527 Acetyltransf_9 Acetyltransferase (GNAT) domain
AAA PF13530 SCP2_2 Sterol carrier protein domain
AAA PF17668 Acetyltransf_17 Acetyltransferase (GNAT) domain
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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