6XMJC

Human 20s proteasome bound to an engineered 11s (pa26) activator
Total Genus 55
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
55
sequence length
244
structure length
244
Chain Sequence
RTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords Proteasome subunit alpha type-6
publication title The Yphi Motif Defines the Structure-Activity Relationships of Human 20S Proteasome Activators
rcsb
source organism Homo sapiens
total genus 55
structure length 244
sequence length 244
ec nomenclature ec 3.4.25.1: Proteasome endopeptidase complex.
pdb deposition date 2020-06-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00227 Proteasome Proteasome subunit
C PF10584 Proteasome_A_N Proteasome subunit A N-terminal signature
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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