6YGJB

Small-molecule stabilizer of 14-3-3 and the carbohydrate response element binding protein (chrebp) protein-protein interaction
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
20
structure length
20
Chain Sequence
RDKIRLNNAIWRAWYIQYVQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Structural protein
molecule keywords 14-3-3 protein beta/alpha
publication title Structure-based evolution of a promiscuous inhibitor to a selective stabilizer of protein-protein interactions.
pubmed doi rcsb
source organism Homo sapiens
total genus 5
structure length 20
sequence length 20
chains with identical sequence I
ec nomenclature
pdb deposition date 2020-03-27
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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