7GEPA

Sulfite reductase hemoprotein in complex with a partially oxidized sulfide species
Total Genus 161
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
161
sequence length
490
structure length
469
Chain Sequence
LLRCRLPGGVITTKQWQAIDKFAGENTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALNDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKAEVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDDNWHLTLFIENGRILDYPARPLKTGLLEIAKIHKGDFRITANQNLIIAGVPESEKAKIEKIAKESGLMNAVTPQRENSMACVSFPTCPLAMAEAERFLPSFIDNIDNLMAKHGVSDEHIVMRVTGCPNGCGRAMLAEVGLVGKAPGRYNLHLGGNRIGTRIPRMYKENITEPEILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDLWD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Probing the catalytic mechanism of sulfite reductase by X-ray crystallography: structures of the Escherichia coli hemoprotein in complex with substrates, inhibitors, intermediates, and products.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Oxidoreductase
molecule keywords SULFITE REDUCTASE HEMOPROTEIN
total genus 161
structure length 469
sequence length 490
ec nomenclature ec 1.8.1.2: Assimilatory sulfite reductase (NADPH).
pdb deposition date 1997-07-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01077 NIR_SIR Nitrite and sulphite reductase 4Fe-4S domain
A PF03460 NIR_SIR_ferr Nitrite/Sulfite reductase ferredoxin-like half domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.413.10 Alpha Beta 2-Layer Sandwich Sulfite Reductase Hemoprotein; domain 1 Sulfite Reductase Hemoprotein, domain 1 7gepA01
3.30.413.10 Alpha Beta 2-Layer Sandwich Sulfite Reductase Hemoprotein; domain 1 Sulfite Reductase Hemoprotein, domain 1 7gepA03
3.90.480.10 Alpha Beta Alpha-Beta Complex Sulfite Reductase Hemoprotein; domain 2 Sulfite Reductase Hemoprotein;Domain 2 7gepA02
2V4JA 3MM5A 3VKPA 4S3EA 3VKSA 8GEPA 6GEPA 3MM6A 3MMBA 1ZJ8A 3VKQA 3OR2A 1AOPA 3OR2B 3MMBB 5AOPA 3MM9B 3MM9A 4S38A 4S3DA 4S3BA 1ZJ9A 4HTRA 4GEPA 3MM7A 3OR1B 3NOYA 3VKRA 3MM5B 4S3CA 3B0GA 2V4JB 3VLXA 3MM7B 3AOPA 4S23A 4G38A 3B0JA 3B0HA 2GEPA 3MM6B 4S3FA 4S39A 7GEPA 4G9PA 3VLZA 2AOPA 3MM8B 3MMAB 5GEPA 2XSJA 2XSJB 2Y0FA 3B0NA 3GEOA 3MMAA 3MM8A 4G39A 3VKTA 3VM0A 3VLYA 3OR1A 3B0MA 3B0LA 3MMCA 4AOPA 3VM1A 2AKJA 3MMCB 4S3AA
chains in the Genus database with same CATH superfamily
2V4JA 3MM5A 3VKPA 4S3EA 3VKSA 8GEPA 6GEPA 3MM6A 3MMBA 1ZJ8A 3VKQA 3OR2A 1AOPA 3OR2B 3MMBB 5AOPA 3MM9B 3MM9A 4S38A 4S3DA 4S3BA 1ZJ9A 4HTRA 4GEPA 3MM7A 3OR1B 3NOYA 3VKRA 3MM5B 4S3CA 3B0GA 2V4JB 3VLXA 3MM7B 3AOPA 4S23A 4G38A 3B0JA 3B0HA 2GEPA 3MM6B 4S3FA 4S39A 7GEPA 4G9PA 3VLZA 2AOPA 3MM8B 3MMAB 5GEPA 2XSJA 2XSJB 2Y0FA 3B0NA 3GEOA 3MMAA 3MM8A 4G39A 3VKTA 3VM0A 3VLYA 3OR1A 3B0MA 3B0LA 3MMCA 4AOPA 3VM1A 2AKJA 3MMCB 4S3AA
chains in the Genus database with same CATH topology
2V4JA 3MM5A 3VKPA 4S3EA 3VKSA 8GEPA 6GEPA 3MM6A 3MMBA 1ZJ8A 3VKQA 3OR2A 1AOPA 3OR2B 3MMBB 5AOPA 3MM9B 3MM9A 4S38A 4S3DA 4S3BA 1ZJ9A 4HTRA 4GEPA 3MM7A 3OR1B 3NOYA 3VKRA 3MM5B 4S3CA 3B0GA 2V4JB 3VLXA 3MM7B 3AOPA 4S23A 4G38A 3B0JA 3B0HA 2GEPA 3MM6B 4S3FA 4S39A 7GEPA 4G9PA 3VLZA 2AOPA 3MM8B 3MMAB 5GEPA 2XSJA 2XSJB 2Y0FA 3B0NA 3GEOA 3MMAA 3MM8A 4G39A 3VKTA 3VM0A 3VLYA 3OR1A 3B0MA 3B0LA 3MMCA 4AOPA 3VM1A 2AKJA 3MMCB 4S3AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2V4J A;  3MM5 A;  3VKP A;  4S3E A;  3VKS A;  8GEP A;  6GEP A;  3MM6 A;  3MMB A;  1ZJ8 A;  3VKQ A;  3OR2 A;  1AOP A;  3OR2 B;  3MMB B;  5AOP A;  3MM9 B;  3MM9 A;  4S38 A;  4S3D A;  4S3B A;  1ZJ9 A;  4HTR A;  4GEP A;  3MM7 A;  3OR1 B;  3NOY A;  3VKR A;  3MM5 B;  4S3C A;  3B0G A;  2V4J B;  3VLX A;  3MM7 B;  3AOP A;  4S23 A;  4G38 A;  3B0J A;  3B0H A;  2GEP A;  3MM6 B;  4S3F A;  4S39 A;  7GEP A;  4G9P A;  3VLZ A;  2AOP A;  3MM8 B;  3MMA B;  5GEP A;  2XSJ A;  2XSJ B;  2Y0F A;  3B0N A;  3GEO A;  3MMA A;  3MM8 A;  4G39 A;  3VKT A;  3VM0 A;  3VLY A;  3OR1 A;  3B0M A;  3B0L A;  3MMC A;  4AOP A;  3VM1 A;  2AKJ A;  3MMC B;  4S3A A; 
#chains in the Genus database with same CATH topology
 2V4J A;  3MM5 A;  3VKP A;  4S3E A;  3VKS A;  8GEP A;  6GEP A;  3MM6 A;  3MMB A;  1ZJ8 A;  3VKQ A;  3OR2 A;  1AOP A;  3OR2 B;  3MMB B;  5AOP A;  3MM9 B;  3MM9 A;  4S38 A;  4S3D A;  4S3B A;  1ZJ9 A;  4HTR A;  4GEP A;  3MM7 A;  3OR1 B;  3NOY A;  3VKR A;  3MM5 B;  4S3C A;  3B0G A;  2V4J B;  3VLX A;  3MM7 B;  3AOP A;  4S23 A;  4G38 A;  3B0J A;  3B0H A;  2GEP A;  3MM6 B;  4S3F A;  4S39 A;  7GEP A;  4G9P A;  3VLZ A;  2AOP A;  3MM8 B;  3MMA B;  5GEP A;  2XSJ A;  2XSJ B;  2Y0F A;  3B0N A;  3GEO A;  3MMA A;  3MM8 A;  4G39 A;  3VKT A;  3VM0 A;  3VLY A;  3OR1 A;  3B0M A;  3B0L A;  3MMC A;  4AOP A;  3VM1 A;  2AKJ A;  3MMC B;  4S3A A; 
#chains in the Genus database with same CATH homology
 2V4J A;  3MM5 A;  3VKP A;  4S3E A;  3VKS A;  8GEP A;  6GEP A;  3MM6 A;  3MMB A;  1ZJ8 A;  3VKQ A;  3OR2 A;  1AOP A;  3OR2 B;  3MMB B;  5AOP A;  3MM9 B;  3MM9 A;  4S38 A;  4S3D A;  4S3B A;  1ZJ9 A;  4HTR A;  4GEP A;  3MM7 A;  3OR1 B;  3NOY A;  3VKR A;  3MM5 B;  4S3C A;  3B0G A;  2V4J B;  3VLX A;  3MM7 B;  3AOP A;  4S23 A;  4G38 A;  3B0J A;  3B0H A;  2GEP A;  3MM6 B;  4S3F A;  4S39 A;  7GEP A;  4G9P A;  3VLZ A;  2AOP A;  3MM8 B;  3MMA B;  5GEP A;  2XSJ A;  2XSJ B;  2Y0F A;  3B0N A;  3GEO A;  3MMA A;  3MM8 A;  4G39 A;  3VKT A;  3VM0 A;  3VLY A;  3OR1 A;  3B0M A;  3B0L A;  3MMC A;  4AOP A;  3VM1 A;  2AKJ A;  3MMC B;  4S3A A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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