7ALVA

Crystal structure of nlrp3 nacht domain in complex with a potent inhibitor
Total Genus 147
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
147
sequence length
543
structure length
472
Chain Sequence
KDYRKKYRKYVRSRFQCIELNKRYTRLRLIKEHSPIKMELLFDPDEPVHTVVFQGAAGIGKTILARKMMLDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFLMDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCTGLKQQMESGKSLAQTSKTTTAVYVFFLSSLLCAHLWGLCSLAADGIWNQKILFEESDLRNHGLQDVSAFLRMNLFQKEVKFYSFIHMTFQEFFAAMYYLLEESRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERSYLEKKLSCKISQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTRMDHMVSSFCIENCHRV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Immune system
molecule keywords NACHT, LRR and PYD domains-containing protein 3
publication title Crystal structure of NLRP3 NACHT domain with an inhibitor defines mechanism of inflammasome inhibition
rcsb
source organism Homo sapiens
total genus 147
structure length 472
sequence length 543
ec nomenclature
pdb deposition date 2020-10-07
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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