7APKH

Structure of the human tho - uap56 complex
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
170
structure length
170
Chain Sequence
KLTLHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNISELPDEIDISSYIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Gene regulation
molecule keywords THO complex subunit 1
publication title Structure of the human core transcription-export complex reveals a hub for multivalent interactions.
pubmed doi rcsb
source organism Homo sapiens
total genus 39
structure length 170
sequence length 170
chains with identical sequence P, h, p
ec nomenclature ec 3.6.4.13: RNA helicase.
pdb deposition date 2020-10-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
H PF00270 DEAD DEAD/DEAH box helicase
H PF00271 Helicase_C Helicase conserved C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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