7AT8F

Histone h3 recognition by nucleosome-bound prc2 subunit ezh2.
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
103
structure length
103
Chain Sequence
b'TRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNIQSVLLPK'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Isoform 2 of Histone-lysine N-methyltransferase EZH2,Isoform
publication title Structural basis for PRC2 decoding of active histone methylation marks H3K36me2/3.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Gene regulation
total genus 22
structure length 103
sequence length 103
chains with identical sequence J
ec nomenclature
pdb deposition date 2020-10-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00125 Histone Core histone H2A/H2B/H3/H4
F PF16211 Histone_H2A_C C-terminus of histone H2A
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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