7B7UA

Cryo-em structure of mammalian rna polymerase ii in complex with human rpap2
Total Genus 269
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
269
sequence length
1056
structure length
986
Chain Sequence
FSARTVITPDPNLSIDQVGVPRSIAANMTFAEIVTPFNIDRLQELVRRGNSQYPGAKYIIRDNGDRIDLLHLQTGYKVERHMCDGDIVIFMGHRVRILPWSTFRLNLSVTEMNLHLPQSLETRAEIQELAIVQDTLTAVRKFTKRDVFLERGEVMNLLMFLSTWDGKVPQPAILKPRPLWTGKQIFSLIIPGHINCIRTHSTHPDDEDSGPYKHISPGDTKVVVENGELIMGILCKKSLGTSAGSLVHISYLEMGHDITRLFYSNIQTVINNWLLIEGHTIGIGDSIADSKTYQDIQNTIKKAKQDVIEVIEKAHNNELEPTPGNTLRQTFENQVNRILNDARDKTGSSAQKSLSEYNNFKSMVVSGAKGSKINISQVIAVVGQQNVEGKRIPFGFKHRTLPHFIKDDYGPESRGFVENSYLAGLTPTEFFFHAMGGREGLIDTAVKTAETGYIQRRLIKSMESVMVKYDATVRNSINQVVQLRYGEDGLAGESVEFQNLATLKPSNKAFEKKFRFDYTNERALRRTLQEDLVKDVLSNAHIQNELEREFERMREDREVLRVIFPTGDSKVVLPCNLLRMIWNAQKIFHINPRLPSDLHPIKVVEGVKELSKKLVIVNGDDPLSRQAQENATLLFNIHLRSTLCSRRMAEEFRLSGEAFDWLLGEIESKFNQAIAHPGEMVGALAAQSLGEPATQMTKNVTLGVPRLKELINISKKPKTPSLTVFLLGQSARDAERAKDILCRLEHTTLRKVTANTAIYYDPNPQSTVVAEDQEWVNVYYEMPDFDVARISPWLLRVELDRKHMTDRKLTMEQIAEKINAGFGDDLNCIFNDDNAEKLVLRIRIMNSKMDDDVFLRCIESNMLTDMTLQGIEQISKVYMHLPQTDNKKKIIITEDGEFKALQEWILETDGVSLMRVLSEKDVDPVRTTSNDIVEIFTVLGIEAVRKALERELYHVISFDGSYVNYRHLALLCDTMTCRGHLMAITR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Transcription
molecule keywords DNA-directed RNA polymerase subunit
publication title Cryo-EM structure of mammalian RNA polymerase II in complex with human RPAP2
doi rcsb
source organism Homo sapiens
total genus 269
structure length 986
sequence length 1056
ec nomenclature
pdb deposition date 2020-12-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00623 RNA_pol_Rpb1_2 RNA polymerase Rpb1, domain 2
A PF04983 RNA_pol_Rpb1_3 RNA polymerase Rpb1, domain 3
A PF04990 RNA_pol_Rpb1_7 RNA polymerase Rpb1, domain 7
A PF04992 RNA_pol_Rpb1_6 RNA polymerase Rpb1, domain 6
A PF04997 RNA_pol_Rpb1_1 RNA polymerase Rpb1, domain 1
A PF04998 RNA_pol_Rpb1_5 RNA polymerase Rpb1, domain 5
A PF05000 RNA_pol_Rpb1_4 RNA polymerase Rpb1, domain 4
A PF05001 RNA_pol_Rpb1_R RNA polymerase Rpb1 C-terminal repeat
Image from the rcsb pdb (www.rcsb.org)
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