7DCOS

Cryo-em structure of the activated spliceosome (bact complex) at an atomic resolution of 2.5 angstrom
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
173
structure length
71
Chain Sequence
TSHRPQLEARSGAKAAAYTPTGIEHARLLPGHTTLKYRKRSWRKGTAFGRGYINDMTKSEYHQEFLHKHVR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Splicing
molecule keywords PRP8 isoform 1
publication title Mechanism of spliceosome remodeling by the ATPase/helicase Prp2 and its coactivator Spp2.
pubmed doi rcsb
total genus 5
structure length 71
sequence length 173
ec nomenclature
pdb deposition date 2020-10-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
S PF04889 Cwf_Cwc_15 Cwf15/Cwc15 cell cycle control protein
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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