7DCOw

Cryo-em structure of the activated spliceosome (bact complex) at an atomic resolution of 2.5 angstrom
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
140
structure length
127
Chain Sequence
SRRDMEVIKLTARYYAKDKSIVEQMISKDGEARLNFMNSSHPLHKTFTDFVAQYKRVYSFTGQEIKKSKRTILDNCFERTQYWEFEKDKDREHDKLVELCKIQFAAIPWDKFTQVAKFDLEQMRLRR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Splicing
molecule keywords PRP8 isoform 1
publication title Mechanism of spliceosome remodeling by the ATPase/helicase Prp2 and its coactivator Spp2.
pubmed doi rcsb
total genus 30
structure length 127
sequence length 140
ec nomenclature
pdb deposition date 2020-10-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
w PF01805 Surp Surp module
w PF12230 PRP21_like_P Pre-mRNA splicing factor PRP21 like protein
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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