7DPQA

Hiv-1 protease d30n mutant
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
203
structure length
196
Chain Sequence
PQVTLWQRPLVTIKIGGQLKEALLDTGADNTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEIGHKAIGTVLVGPTPVNIIGRNLLTQIGMTLNFPQVTLWQRPLVTIKIGGQLKEALLDTGADNTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEIGHKAIGTVLVGPTPVNIIGRNLLTQIGATLNF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Viral protein
molecule keywords Protease
publication title Molecular basis for reduced cleavage activity and drug resistance in D30N HIV-1 protease.
pubmed doi rcsb
source organism Human immunodeficiency virus 1
total genus 46
structure length 196
sequence length 203
ec nomenclature
pdb deposition date 2020-12-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00077 RVP Retroviral aspartyl protease
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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