7EH0F

Thermus thermophilus rna polymerase transcription initiation complex containing a template-strand purine at position tss-2, upa rna primer and cmpcpp
Total Genus 121
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
121
sequence length
346
structure length
346
Chain Sequence
SDPVRQYLHEIGQVPLLTLEEEVELARKVEEGMEAIKKLSEITGLDPDLIREVVRAKILGSARVRHIPGLKETLDPKTVEEIDQKLKSLPKEHKRYLHIAREGEAARQHLIEANLRLVVSIAKKYTGRGLSFLDLIQEGNQGLIRAVEKFEYKRRFKFSTYATWWIRQAINRAIADQARTIRIPVHMVETINKLSRTARQLQQELGREPTYEEIAEAMGPGWDAKRVEETLKIAQEPVSLETPIGDEKDSFYGDFIPDEHLPSPVDAATQSLLSEELEKALSKLSEREAMVLKLRKGLIDGREHTLEEVGAFFGVTRERIRQIENKALRKLKYHESRTRKLRDFLD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transcription/dna/rna
molecule keywords DNA-directed RNA polymerase subunit alpha
publication title Promoter-sequence determinants and structural basis of primer-dependent transcription initiation in Escherichia coli .
pubmed doi rcsb
source organism Thermus thermophilus hb8
total genus 121
structure length 346
sequence length 346
ec nomenclature
pdb deposition date 2021-03-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00140 Sigma70_r1_2 Sigma-70 factor, region 1.2
F PF04539 Sigma70_r3 Sigma-70 region 3
F PF04542 Sigma70_r2 Sigma-70 region 2
F PF04545 Sigma70_r4 Sigma-70, region 4
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the pdb database (?% sequence similarity)

 
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