7JHPC

Crystal structure of hras in complex with the ras-binding and cysteine-rich domains of craf-kinase
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
133
structure length
126
Chain Sequence
SNTIRVFLPNKQRTVVNVRNGMSLHDCLMKALKVRGLQPECCAVFRLLKKARLDWNTDAASLIGEELQVDFLDHLTTHNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVPTMCVDW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
molecule keywords GTPase HRas
publication title Crystal structure reveals the full Ras:Raf interface and advances mechanistic understanding of Raf activation
doi rcsb
source organism Homo sapiens
total genus 20
structure length 126
sequence length 133
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2020-07-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00130 C1_1 Phorbol esters/diacylglycerol binding domain (C1 domain)
C PF02196 RBD Raf-like Ras-binding domain
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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