7JPOC

Orc-o1aaa: human origin recognition complex (orc) with dynamic/unresolved orc2 wh
Total Genus 159
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
159
sequence length
707
structure length
594
Chain Sequence
TSSMSKGCFVFKPNSKKRKISLPIEDYFNKGKNEPEDSKLRFETYQLIWQQMKSENERLQEELNKNLFDNLIEFLQKSHSGFQKNLREIPTAALVLGVNVTDHDLTFGSLTEALQNNVTPYVVSLQAKDCPDMKHFLQKLISQLMDCTHYSMDSLSSWYMTVTQSPPVVVILKDMESFATKVLQDFIIISSQHLHEFPLILIFGIATSPIIIHRLLPHAVSSLLCIELFQSLSCKEHLTTVLDKLLLTTQFPFKINEKVLQVLTNIFLYHDFSVQNFIKGLQLSLLEHFYSQPLSVLCCNLPEAKRRINFLSNNQCENIRRLPSFRRYVEKQASEKQVALLTNERYLKEETQLLLENLHVYHMNYFLVLRCLHKFTSSLPKYPLGRQIRELYCTCLEKNIWDSEEYASVLQLLRMLAKDELMTILEKCFKVFKSYCENHLGSTAKRIEEFLAQFKFEVLRENVVNFIDCLVREYLLPPETQPLHEVVYFSAAHALREHLNAAPRIALHTALNNPYYYLKNEALKSNIAPDICIAYKLHLINLVDWSEAFATVVTAAEMNEIIHARFIRAVSELELLGFIKPTKQKTDHVARLTW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Replication
molecule keywords Origin recognition complex subunit 1
publication title The dynamic nature of the human Origin Recognition Complex revealed through five cryoEM structures.
pubmed doi rcsb
source organism Homo sapiens
total genus 159
structure length 594
sequence length 707
ec nomenclature
pdb deposition date 2020-08-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF07034 ORC3_N Origin recognition complex (ORC) subunit 3 N-terminus
C PF18137 ORC_WH_C Origin recognition complex winged helix C-terminal
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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