7JT4A

Crystal structure of bptf bromodomain labelled with 5-fluoro-tryptophan
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
122
structure length
121
Chain Sequence
MSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLKGFKASRSH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Gene regulation
molecule keywords Nucleosome-remodeling factor subunit BPTF
publication title Selectivity, ligand deconstruction, and cellular activity analysis of a BPTF bromodomain inhibitor
pubmed doi rcsb
source organism Homo sapiens
total genus 46
structure length 121
sequence length 122
ec nomenclature
pdb deposition date 2020-08-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00439 Bromodomain Bromodomain
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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