7JTWA

Crystal structure of rorgt with compound (4r)-6-[(2,5-dichloro-3-{[(2r,4r)-1-(cyclopentanecarbonyl)-2-methylpiperidin-4-yl]oxy}phenyl)amino]-6-oxo-4-phenylhexanoic acid
Total Genus 102
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
102
sequence length
259
structure length
259
Chain Sequence
ASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERMQIFQHLHPIVVQAAFPPLYKELFSTGGSGDHKIIHRLLQE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Nuclear protein
molecule keywords RAR-related orphan receptor C isoform a variant
publication title Discovery of 6-Oxo-4-Phenyl-Hexanoic Acid Derivatives as RORgammat Inverse Agonists Showing Favorable ADME Profile
doi rcsb
source organism Homo sapiens
total genus 102
structure length 259
sequence length 259
ec nomenclature
pdb deposition date 2020-08-18
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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