7K62A

Crystal structure of dihydrofolate reductase from mycobacterium kansasii in complex with nadp and inhibitor p218
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
165
structure length
165
Chain Sequence
HHHHHHMVGLIWAQSTSGVIGRGGDIPWRVPEDLSHFKRITMGHTVVMGRRTWDSLPASARPLPGRRNVVLSRQPGFVAEGAEVVGSLEDALTGPEDTWVIGGEQIYTLALPRAIRCEVTEVDVDLPRDDDDALAPPLDETWQGDVGEWQVSRSGLRYRFHSYYR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase/oxidoreductase inhibitor
molecule keywords Dihydrofolate reductase
publication title Crystal Structure of Dihydrofolate reductase from Mycobacterium kansasii in complex with NADP and inhibitor P218
rcsb
source organism Mycobacterium kansasii
total genus 45
structure length 165
sequence length 165
chains with identical sequence B
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2020-09-18
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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