7KR5H

Cryo-em structure of the crac channel orai in an open conformation; h206a gain-of-function mutation in complex with an antibody
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
121
structure length
116
Chain Sequence
VQLVESGGGLVQPKGSLKLSCAASGFTFNTYAMHWVRQAKGLEWVARIRTNYATYYADSVKDRFTISRDDSQSMLYLQMNNLKTEDTAMYYCVRQKYGNYFDYWGQGTTLTVSSAK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transport protein/immune system
molecule keywords Calcium release-activated calcium channel protein 1
publication title Cryo-EM structure of the calcium release-activated calcium channel Orai in an open conformation.
pubmed doi rcsb
source organism Drosophila melanogaster
total genus 13
structure length 116
sequence length 121
chains with identical sequence M, O
ec nomenclature
pdb deposition date 2020-11-18
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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