7LJCR

Allosteric modulator ly3154207 binding to skf-81297-bound dopamine receptor 1 in complex with minigs protein
Total Genus 106
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
106
sequence length
327
structure length
280
Chain Sequence
SVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
molecule keywords D(1A) dopamine receptor
publication title Mechanism of dopamine binding and allosteric modulation of the human D1 dopamine receptor
doi rcsb
source organism Homo sapiens
total genus 106
structure length 280
sequence length 327
ec nomenclature
pdb deposition date 2021-01-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
R PF00001 7tm_1 7 transmembrane receptor (rhodopsin family)
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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