7NBDAAA

Crystal structure of human serine racemase in complex with dsip fragment z235449082, xchem fragment screen
Total Genus 119
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
119
sequence length
323
structure length
323
Chain Sequence
b'QYDISFADVEKAHINIRDSIHLTPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRSLVPDALERKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQAYGASIVYCEPSDESRENVAKRVTEETEGIMVHPNQEPAVIAGQGTIALEVLNQVPLVDALVVPVGGGGMLAGIAITVKALKPSVKVYAAEPSNADDCYQSKLKGKLMPNLYPPETIADGVKSSIGLNTWPIIRDLVDDIFTVTEDEIKCATQLVWERMKLLIEPTAGVGVAAVLSQHFQTVSPEVKNICIVLSGGNVDLTSSITWV'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Serine racemase
publication title Tyrosine 121 moves revealing a druggable pocket that couples catalysis to ATP-binding in serine racemase
doi rcsb
source organism Homo sapiens
molecule tags Isomerase
total genus 119
structure length 323
sequence length 323
chains with identical sequence BBB, CCC, DDD
ec nomenclature ec 4.3.1.17: L-serine ammonia-lyase.
pdb deposition date 2021-01-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
AAA PF00291 PALP Pyridoxal-phosphate dependent enzyme
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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