7NFCC

Cryo-em structure of nhej super-complex (dimer)
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
532
structure length
477
Chain Sequence
NKAAVVLCMDVGFTMSSPFEQAKKVITMFVQRQVFAENKDEIALVLFGTDGTDNQNITVHRHLMLPDFDLLEDIESKIQPGSQQADFLDALIVSMDVIQHETIGKKFEKRHIEIFQLDIIIHSLKKCDISLQFFLPFSTEQQKEGLEIVKMVMISLEGEDGLDEIYSFSESLRKLCVFKKIERHSIHWPCRLTIGSNLSIRIAAYKSILQERVKKTWTVVDAKTLKKEDIQKETVYCLNDDDETEVLKEDIIQGFRYGSDIVPFSKVDEEQMKYKSEGKCFSVLGFCKSSQVQRRFFMGNQVLKVFAARDEAAAVALSSLIHALDDLDMVAIVRYAYDKRANPQVGVAFPHIKHNYECLVYVQLPFMEDLRQYMFSSLKNSKKYAPTEAQLNAVDALIDSMSLAKKDEKTDTLEDLFPTTKIPNPRFQRLFQCLLHRALHPREPLPPIQQHIWNMLNPPAEVTTKSQIPLSKIKTLF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Dna binding protein
molecule keywords DNA-dependent protein kinase catalytic subunit,DNA-dependent protein kinase catalytic subunit,DNA-PKcs
publication title Cryo-EM of NHEJ supercomplexes provides insights into DNA repair.
pubmed doi rcsb
source organism Homo sapiens
total genus 87
structure length 477
sequence length 532
chains with identical sequence H
ec nomenclature
pdb deposition date 2021-02-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF02735 Ku Ku70/Ku80 beta-barrel domain
C PF03730 Ku_C Ku70/Ku80 C-terminal arm
C PF03731 Ku_N Ku70/Ku80 N-terminal alpha/beta domain
C PF08785 Ku_PK_bind Ku C terminal domain like
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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