7NFCM

Cryo-em structure of nhej super-complex (dimer)
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
258
structure length
258
Chain Sequence
KISNIFEDVEFCVMSGTDSQPKPDLENRIAEFGGYIVQNPGPDTYCVIAGSENIRVKNIILSNKHDVVKPAWLLECFKTKSFVPWQPRFMIHMCPSTKEHFAREYDCYGDSYFIDTDLNQLKEVFSGIKNSNEQTPEEMASLIADLEYRYSWDCSPLSMFRRHTVYLDSYAVINDLSTKNEGTRLAIKALELRFHGAKVVSCLAEGVSHVIIGEDHSRVADFKAFRRTFKRKFKILKESWVTDSIDKCELQEENQYLI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Dna binding protein
molecule keywords DNA-dependent protein kinase catalytic subunit,DNA-dependent protein kinase catalytic subunit,DNA-PKcs
publication title Cryo-EM of NHEJ supercomplexes provides insights into DNA repair.
pubmed doi rcsb
source organism Homo sapiens
total genus 52
structure length 258
sequence length 258
chains with identical sequence P
ec nomenclature ec 6.5.1.1: DNA ligase (ATP).
pdb deposition date 2021-02-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
M PF00533 BRCT BRCA1 C Terminus (BRCT) domain
M PF01068 DNA_ligase_A_M ATP dependent DNA ligase domain
M PF04675 DNA_ligase_A_N DNA ligase N terminus
M PF04679 DNA_ligase_A_C ATP dependent DNA ligase C terminal region
M PF11411 DNA_ligase_IV DNA ligase IV
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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