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X-ray structure of hdm2/cmr19 at 1.45a: discovery, x-ray structure and cpp-conjugation enabled uptake of p53/mdm2 macrocyclic peptide inhibitors
Total Genus 0
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
0
sequence length
13
structure length
10
Chain Sequence
FSDSSVPNRN

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Ligase
molecule keywords E3 ubiquitin-protein ligase Mdm2
publication title Discovery, X-ray structure and CPP-conjugation enabled uptake of p53/MDM2 macrocyclic peptide inhibitors
doi rcsb
source organism Homo sapiens
structure length 10
sequence length 13
chains with identical sequence E, F
ec nomenclature
pdb deposition date 2021-03-13
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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