7OQYB

Cryo-em structure of the cellular negative regulator tfs4 bound to the archaeal rna polymerase
Total Genus 296
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
296
sequence length
1120
structure length
1105
Chain Sequence
MLDTESRWAIAESFFKTRGLVRQHLDSFNDFLRNKLQQVIYEQGEIVTEVPGLKIKLGKIRYEKPSIRETDKGPMREITPMEARLRNLTYSSPIFLSMIPVENNIEGEPIEIYIGDLPIMLKSVADPTSNLPIDKLIEIGEDPKDPGGYFIVNGSEKVIIAQEDLATNRVLVDYGKSGSNITHVAKVTSSAAGYRVQVMIERLKDSTIQISFATVPGRIPFAIIMRALGFVTDRDIVYAVSLDPQIQNELLPSLEQASSITSAEEALDFIGNRVAIGQKRENRIQKAEQVIDKYFLPHLGTSPEDRKKKGYYLASAVNKILELYLGRREPDDKDHYANKRVRLAGDLFTSLFRVAFKAFVKDLVYQLEKSKVRGRRLSLTALVRADIITERIRHALATGNWVGGRTGVSQLLDRTNWLSMLSHLRRVVSSLAPNFEARDLHGTQWGRMCPFETPEGPNSGLVKNLALLAQVSVGINESVVERVAYELGVVSVEDVIRRISEQNEDVEKYMSWSKVYLNGRLLGYYEDGKELAKKIRESRRQGKLSDEVNVAYIATDYLNEVHINCDAGRVRRPLIIVNNGTPLVDTEDIKKLKNGEITFDDLVKQGKIEFIDAEEEENAYVALNPQDLTPDHTHLEIWPSAILGIIASIIPYPEHNQSPRNTYQSAMAKQSLGLYASNYQIRTDTRAHLLHYPQMPLVQTRMLGVIGYNDRPAGANAILAIMSYTGYNMEDSIIMNKSSIERGMYRSTFFRLYSTEEVKYPGGQEDKIITPEAGVKGYKGKDYYRLLEDNGVVSPEVEVKGGDVLIGKVSPPRAKRDTSIVTRHGENGIVDLVLITETLEGNKLVKVRVRDLRIPEIGDKFATRHGQKGVVGILIDQVDMPYTAKGIVPDIILNPHALPSRMTIGQIMEAIGGKYAALSGKPVDATPFLETPKLQEMQKEILKLGHLPDSTEVVYDGRTGQKLKSRILFGIVYYQKLHHMVADKMHARARGPVQILTRQPTEGRAREGGLRFGEMERDCLIGFGTAMLIKDRLLDNSDKAVVYICDQCGYVGWYDRSKNRYVCPVHGDKSVLHPVTVSYAFKLLIQELMSMVISPRLILGEKVNL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Transcription
molecule keywords DNA-directed RNA polymerase subunit A'
publication title Structural basis of RNA polymerase inhibition by viral and host factors.
pubmed doi rcsb
source organism Sulfolobus acidocaldarius dsm 639
total genus 296
structure length 1105
sequence length 1120
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2021-06-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00562 RNA_pol_Rpb2_6 RNA polymerase Rpb2, domain 6
B PF04560 RNA_pol_Rpb2_7 RNA polymerase Rpb2, domain 7
B PF04561 RNA_pol_Rpb2_2 RNA polymerase Rpb2, domain 2
B PF04563 RNA_pol_Rpb2_1 RNA polymerase beta subunit
B PF04565 RNA_pol_Rpb2_3 RNA polymerase Rpb2, domain 3
B PF04566 RNA_pol_Rpb2_4 RNA polymerase Rpb2, domain 4
B PF04567 RNA_pol_Rpb2_5 RNA polymerase Rpb2, domain 5
Image from the rcsb pdb (www.rcsb.org)
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...