7PTIA

Structural effects induced by removal of a disulfide bridge. the x-ray structure of the c30a(slash)c51a mutant of basic pancreatic trypsin inhibitor at 1.6 angstroms
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
58
structure length
58
Chain Sequence
RPDFCLEPPYTGPCKARIIRYFYNAKAGLAQTFVYGGCRAKRNNFKSAEDAMRTCGGA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural effects induced by removal of a disulfide-bridge: the X-ray structure of the C30A/C51A mutant of basic pancreatic trypsin inhibitor at 1.6 A.
pubmed doi rcsb
molecule tags Proteinase inhibitor (trypsin)
source organism Bos taurus
molecule keywords BOVINE PANCREATIC TRYPSIN INHIBITOR
total genus 9
structure length 58
sequence length 58
ec nomenclature
pdb deposition date 1990-03-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00014 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 7ptiA00
1JC6A 1FAKI 3BTKI 1KIGI 1BTIA 3AUEA 4Y0YI 4BNRI 4DTGK 3L33E 1P2KI 2CA7A 2UUXA 3LDJA 4Y0ZI 1OA55 1BHCA 4NTXB 2M99A 4U32X 9PTIA 4TPII 3P92E 1CO7I 5C67C 1QLQA 1UUBA 3U1JE 1TCPA 1KUNA 2ZVXA 4PTIA 4ISNB 4BQDA 5JB4A 1DTXA 1P2OB 1YLCB 1BUNB 1EAWB 2DDIA 1ADZA 3BTMI 3FP7J 3BTEI 2TPII 2KCRA 1G6XA 1T8OB 2RA3C 1BF0A 7PTIA 2LFKA 3TGKI 4U30W 4WWYC 2ODYE 3AUHA 1FY8I 1ZJDB 2TGPI 1TPAI 1UUAA 2FI4I 3T62D 1SHPA 6PTIA 8PTIA 1BRCI 2FI5I 3AUGA 1F5RI 1T8LB 2R9PE 1AALA 3UOUB 3BTDI 2W8XA 3OFWA 1BZXI 1P2II 5JB7A 1P2QB 1P2JI 2FTLI 3AUCA 1CA0D 3GYMI 1YLDB 1BIKA 1BPIA 3M7QB 1BZ5A 5PTIA 3BTGI 1NAGA 2FTMB 4DG4C 3LDIA 4NTWB 1TAWB 5JB6A 1YC0I 2ZJXA 3AUIA 4Y11I 3BTQI 1LD6A 3D65I 3TGII 1DENA 1CBWD 1LD5A 1DTKA 1K6UA 3CI7A 2HEXA 4NTYB 3LDMA 1D0DA 3TPII 1MTND 2KAII 4Y10I 2J6DA 3WNYA 4ISLB 3UIRC 1EJMB 3AUBA 2DDJA 2IJOI 2PTCI 1IRHA 1KNTA 1BTHP 3OTJI 4ISOB 3BYBA 3TGJI 3AUDA 1AAPA 1B0CA 2JOTA 2UUYB 1KTHA 1T8NB 1FANA 1TOCR 3FP6I 2KNTA 3BTFI 1ZR0B 1T7CB 1Y62A 3BTHI 3P95E 1D0DB 3FP8I 4WXVC 1F7ZI 4BD9B 1P2MB 1JV9A 3L3TE 3BTTI 1TFXC 1BPTA 2FI3I 1YKTB 5JB5A 1PITA 1T8MB 1OA65 3BTWI 1DEMA 1TAPA 2LFLA 1JV8A 1BRBI 2M01A 1P2NB
chains in the Genus database with same CATH superfamily
1JC6A 1FAKI 3BTKI 1KIGI 1BTIA 3AUEA 4Y0YI 4BNRI 4DTGK 3L33E 1P2KI 2CA7A 2UUXA 3LDJA 4Y0ZI 1OA55 1BHCA 4NTXB 2M99A 4U32X 9PTIA 4TPII 3P92E 1CO7I 5C67C 1QLQA 1UUBA 3U1JE 1TCPA 1KUNA 2ZVXA 4PTIA 4ISNB 4BQDA 5JB4A 1DTXA 1P2OB 1YLCB 1BUNB 1EAWB 2DDIA 1ADZA 3BTMI 3FP7J 3BTEI 2TPII 2KCRA 1G6XA 1T8OB 2RA3C 1BF0A 7PTIA 2LFKA 3TGKI 4U30W 4WWYC 2ODYE 3AUHA 1FY8I 1ZJDB 2TGPI 1TPAI 1UUAA 2FI4I 3T62D 1SHPA 6PTIA 8PTIA 1BRCI 2FI5I 3AUGA 1F5RI 1T8LB 2R9PE 1AALA 3UOUB 3BTDI 2W8XA 3OFWA 1BZXI 1P2II 5JB7A 1P2QB 1P2JI 2FTLI 3AUCA 1CA0D 3GYMI 1YLDB 1BIKA 1BPIA 3M7QB 1BZ5A 5PTIA 3BTGI 1NAGA 2FTMB 4DG4C 3LDIA 4NTWB 1TAWB 5JB6A 1YC0I 2ZJXA 3AUIA 4Y11I 3BTQI 1LD6A 3D65I 3TGII 1DENA 1CBWD 1LD5A 1DTKA 1K6UA 3CI7A 2HEXA 4NTYB 3LDMA 1D0DA 3TPII 1MTND 2KAII 4Y10I 2J6DA 3WNYA 4ISLB 3UIRC 1EJMB 3AUBA 2DDJA 2IJOI 2PTCI 1IRHA 1KNTA 1BTHP 3OTJI 4ISOB 3BYBA 3TGJI 3AUDA 1AAPA 1B0CA 2JOTA 2UUYB 1KTHA 1T8NB 1FANA 1TOCR 3FP6I 2KNTA 3BTFI 1ZR0B 1T7CB 1Y62A 3BTHI 3P95E 1D0DB 3FP8I 4WXVC 1F7ZI 4BD9B 1P2MB 1JV9A 3L3TE 3BTTI 1TFXC 1BPTA 2FI3I 1YKTB 5JB5A 1PITA 1T8MB 1OA65 3BTWI 1DEMA 1TAPA 2LFLA 1JV8A 1BRBI 2M01A 1P2NB
chains in the Genus database with same CATH topology
1JC6A 1FAKI 3BTKI 1KIGI 1BTIA 3AUEA 4Y0YI 4BNRI 4DTGK 3L33E 1P2KI 2CA7A 2UUXA 3LDJA 4Y0ZI 1OA55 1BHCA 4NTXB 2M99A 4U32X 9PTIA 4TPII 3P92E 1CO7I 5C67C 1QLQA 1UUBA 3U1JE 1TCPA 1KUNA 2ZVXA 4PTIA 4ISNB 4BQDA 5JB4A 1DTXA 1P2OB 1YLCB 1BUNB 1EAWB 2DDIA 1ADZA 3BTMI 3FP7J 3BTEI 2TPII 2KCRA 1G6XA 1T8OB 2RA3C 1BF0A 7PTIA 2LFKA 3TGKI 4U30W 4WWYC 2ODYE 3AUHA 1FY8I 1ZJDB 2TGPI 1TPAI 1UUAA 2FI4I 3T62D 1SHPA 6PTIA 8PTIA 1BRCI 2FI5I 3AUGA 1F5RI 1T8LB 2R9PE 1AALA 3UOUB 3BTDI 2W8XA 3OFWA 1BZXI 1P2II 5JB7A 1P2QB 1P2JI 2FTLI 3AUCA 1CA0D 3GYMI 1YLDB 1BIKA 1BPIA 3M7QB 1BZ5A 5PTIA 3BTGI 1NAGA 2FTMB 4DG4C 3LDIA 4NTWB 1TAWB 5JB6A 1YC0I 2ZJXA 3AUIA 4Y11I 3BTQI 1LD6A 3D65I 3TGII 1DENA 1CBWD 1LD5A 1DTKA 1K6UA 3CI7A 2HEXA 4NTYB 3LDMA 1D0DA 3TPII 1MTND 2KAII 4Y10I 2J6DA 3WNYA 4ISLB 3UIRC 1EJMB 3AUBA 2DDJA 2IJOI 2PTCI 1IRHA 1KNTA 1BTHP 3OTJI 4ISOB 3BYBA 3TGJI 3AUDA 1AAPA 1B0CA 2JOTA 2UUYB 1KTHA 1T8NB 1FANA 1TOCR 3FP6I 2KNTA 3BTFI 1ZR0B 1T7CB 1Y62A 3BTHI 3P95E 1D0DB 3FP8I 4WXVC 1F7ZI 4BD9B 1P2MB 1JV9A 3L3TE 3BTTI 1TFXC 1BPTA 2FI3I 1YKTB 5JB5A 1PITA 1T8MB 1OA65 3BTWI 1DEMA 1TAPA 2LFLA 1JV8A 1BRBI 2M01A 1P2NB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JC6 A;  1FAK I;  3BTK I;  1KIG I;  1BTI A;  3AUE A;  4Y0Y I;  4BNR I;  4DTG K;  3L33 E;  1P2K I;  2CA7 A;  2UUX A;  3LDJ A;  4Y0Z I;  1OA5 5;  1BHC A;  4NTX B;  2M99 A;  4U32 X;  9PTI A;  4TPI I;  3P92 E;  1CO7 I;  5C67 C;  1QLQ A;  1UUB A;  3U1J E;  1TCP A;  1KUN A;  2ZVX A;  4PTI A;  4ISN B;  4BQD A;  5JB4 A;  1DTX A;  1P2O B;  1YLC B;  1BUN B;  1EAW B;  2DDI A;  1ADZ A;  3BTM I;  3FP7 J;  3BTE I;  2TPI I;  2KCR A;  1G6X A;  1T8O B;  2RA3 C;  1BF0 A;  7PTI A;  2LFK A;  3TGK I;  4U30 W;  4WWY C;  2ODY E;  3AUH A;  1FY8 I;  1ZJD B;  2TGP I;  1TPA I;  1UUA A;  2FI4 I;  3T62 D;  1SHP A;  6PTI A;  8PTI A;  1BRC I;  2FI5 I;  3AUG A;  1F5R I;  1T8L B;  2R9P E;  1AAL A;  3UOU B;  3BTD I;  2W8X A;  3OFW A;  1BZX I;  1P2I I;  5JB7 A;  1P2Q B;  1P2J I;  2FTL I;  3AUC A;  1CA0 D;  3GYM I;  1YLD B;  1BIK A;  1BPI A;  3M7Q B;  1BZ5 A;  5PTI A;  3BTG I;  1NAG A;  2FTM B;  4DG4 C;  3LDI A;  4NTW B;  1TAW B;  5JB6 A;  1YC0 I;  2ZJX A;  3AUI A;  4Y11 I;  3BTQ I;  1LD6 A;  3D65 I;  3TGI I;  1DEN A;  1CBW D;  1LD5 A;  1DTK A;  1K6U A;  3CI7 A;  2HEX A;  4NTY B;  3LDM A;  1D0D A;  3TPI I;  1MTN D;  2KAI I;  4Y10 I;  2J6D A;  3WNY A;  4ISL B;  3UIR C;  1EJM B;  3AUB A;  2DDJ A;  2IJO I;  2PTC I;  1IRH A;  1KNT A;  1BTH P;  3OTJ I;  4ISO B;  3BYB A;  3TGJ I;  3AUD A;  1AAP A;  1B0C A;  2JOT A;  2UUY B;  1KTH A;  1T8N B;  1FAN A;  1TOC R;  3FP6 I;  2KNT A;  3BTF I;  1ZR0 B;  1T7C B;  1Y62 A;  3BTH I;  3P95 E;  1D0D B;  3FP8 I;  4WXV C;  1F7Z I;  4BD9 B;  1P2M B;  1JV9 A;  3L3T E;  3BTT I;  1TFX C;  1BPT A;  2FI3 I;  1YKT B;  5JB5 A;  1PIT A;  1T8M B;  1OA6 5;  3BTW I;  1DEM A;  1TAP A;  2LFL A;  1JV8 A;  1BRB I;  2M01 A;  1P2N B; 
#chains in the Genus database with same CATH topology
 1JC6 A;  1FAK I;  3BTK I;  1KIG I;  1BTI A;  3AUE A;  4Y0Y I;  4BNR I;  4DTG K;  3L33 E;  1P2K I;  2CA7 A;  2UUX A;  3LDJ A;  4Y0Z I;  1OA5 5;  1BHC A;  4NTX B;  2M99 A;  4U32 X;  9PTI A;  4TPI I;  3P92 E;  1CO7 I;  5C67 C;  1QLQ A;  1UUB A;  3U1J E;  1TCP A;  1KUN A;  2ZVX A;  4PTI A;  4ISN B;  4BQD A;  5JB4 A;  1DTX A;  1P2O B;  1YLC B;  1BUN B;  1EAW B;  2DDI A;  1ADZ A;  3BTM I;  3FP7 J;  3BTE I;  2TPI I;  2KCR A;  1G6X A;  1T8O B;  2RA3 C;  1BF0 A;  7PTI A;  2LFK A;  3TGK I;  4U30 W;  4WWY C;  2ODY E;  3AUH A;  1FY8 I;  1ZJD B;  2TGP I;  1TPA I;  1UUA A;  2FI4 I;  3T62 D;  1SHP A;  6PTI A;  8PTI A;  1BRC I;  2FI5 I;  3AUG A;  1F5R I;  1T8L B;  2R9P E;  1AAL A;  3UOU B;  3BTD I;  2W8X A;  3OFW A;  1BZX I;  1P2I I;  5JB7 A;  1P2Q B;  1P2J I;  2FTL I;  3AUC A;  1CA0 D;  3GYM I;  1YLD B;  1BIK A;  1BPI A;  3M7Q B;  1BZ5 A;  5PTI A;  3BTG I;  1NAG A;  2FTM B;  4DG4 C;  3LDI A;  4NTW B;  1TAW B;  5JB6 A;  1YC0 I;  2ZJX A;  3AUI A;  4Y11 I;  3BTQ I;  1LD6 A;  3D65 I;  3TGI I;  1DEN A;  1CBW D;  1LD5 A;  1DTK A;  1K6U A;  3CI7 A;  2HEX A;  4NTY B;  3LDM A;  1D0D A;  3TPI I;  1MTN D;  2KAI I;  4Y10 I;  2J6D A;  3WNY A;  4ISL B;  3UIR C;  1EJM B;  3AUB A;  2DDJ A;  2IJO I;  2PTC I;  1IRH A;  1KNT A;  1BTH P;  3OTJ I;  4ISO B;  3BYB A;  3TGJ I;  3AUD A;  1AAP A;  1B0C A;  2JOT A;  2UUY B;  1KTH A;  1T8N B;  1FAN A;  1TOC R;  3FP6 I;  2KNT A;  3BTF I;  1ZR0 B;  1T7C B;  1Y62 A;  3BTH I;  3P95 E;  1D0D B;  3FP8 I;  4WXV C;  1F7Z I;  4BD9 B;  1P2M B;  1JV9 A;  3L3T E;  3BTT I;  1TFX C;  1BPT A;  2FI3 I;  1YKT B;  5JB5 A;  1PIT A;  1T8M B;  1OA6 5;  3BTW I;  1DEM A;  1TAP A;  2LFL A;  1JV8 A;  1BRB I;  2M01 A;  1P2N B; 
#chains in the Genus database with same CATH homology
 1JC6 A;  1FAK I;  3BTK I;  1KIG I;  1BTI A;  3AUE A;  4Y0Y I;  4BNR I;  4DTG K;  3L33 E;  1P2K I;  2CA7 A;  2UUX A;  3LDJ A;  4Y0Z I;  1OA5 5;  1BHC A;  4NTX B;  2M99 A;  4U32 X;  9PTI A;  4TPI I;  3P92 E;  1CO7 I;  5C67 C;  1QLQ A;  1UUB A;  3U1J E;  1TCP A;  1KUN A;  2ZVX A;  4PTI A;  4ISN B;  4BQD A;  5JB4 A;  1DTX A;  1P2O B;  1YLC B;  1BUN B;  1EAW B;  2DDI A;  1ADZ A;  3BTM I;  3FP7 J;  3BTE I;  2TPI I;  2KCR A;  1G6X A;  1T8O B;  2RA3 C;  1BF0 A;  7PTI A;  2LFK A;  3TGK I;  4U30 W;  4WWY C;  2ODY E;  3AUH A;  1FY8 I;  1ZJD B;  2TGP I;  1TPA I;  1UUA A;  2FI4 I;  3T62 D;  1SHP A;  6PTI A;  8PTI A;  1BRC I;  2FI5 I;  3AUG A;  1F5R I;  1T8L B;  2R9P E;  1AAL A;  3UOU B;  3BTD I;  2W8X A;  3OFW A;  1BZX I;  1P2I I;  5JB7 A;  1P2Q B;  1P2J I;  2FTL I;  3AUC A;  1CA0 D;  3GYM I;  1YLD B;  1BIK A;  1BPI A;  3M7Q B;  1BZ5 A;  5PTI A;  3BTG I;  1NAG A;  2FTM B;  4DG4 C;  3LDI A;  4NTW B;  1TAW B;  5JB6 A;  1YC0 I;  2ZJX A;  3AUI A;  4Y11 I;  3BTQ I;  1LD6 A;  3D65 I;  3TGI I;  1DEN A;  1CBW D;  1LD5 A;  1DTK A;  1K6U A;  3CI7 A;  2HEX A;  4NTY B;  3LDM A;  1D0D A;  3TPI I;  1MTN D;  2KAI I;  4Y10 I;  2J6D A;  3WNY A;  4ISL B;  3UIR C;  1EJM B;  3AUB A;  2DDJ A;  2IJO I;  2PTC I;  1IRH A;  1KNT A;  1BTH P;  3OTJ I;  4ISO B;  3BYB A;  3TGJ I;  3AUD A;  1AAP A;  1B0C A;  2JOT A;  2UUY B;  1KTH A;  1T8N B;  1FAN A;  1TOC R;  3FP6 I;  2KNT A;  3BTF I;  1ZR0 B;  1T7C B;  1Y62 A;  3BTH I;  3P95 E;  1D0D B;  3FP8 I;  4WXV C;  1F7Z I;  4BD9 B;  1P2M B;  1JV9 A;  3L3T E;  3BTT I;  1TFX C;  1BPT A;  2FI3 I;  1YKT B;  5JB5 A;  1PIT A;  1T8M B;  1OA6 5;  3BTW I;  1DEM A;  1TAP A;  2LFL A;  1JV8 A;  1BRB I;  2M01 A;  1P2N B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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