7S6BC

Crystal structure of modular polyketide synthase apo-lsd14 from the lasalocid biosynthesis pathway, trapped in the transacylation step
Total Genus 147
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
147
sequence length
530
structure length
510
Chain Sequence
TSAEARFWDAVEDEDLEALVAAIGASWAGVLPALAGWRRRQREQSALDDLRYKVTWKPTAVDGASATGTWLVVVPESLAGGGWPVVVARAVDQAGGRPVVLSVDAADGADRSRLGLRIHEALGEGPVPDAVVSLLALDPSALPGLPDVPQALASTAALVQALLDLGLEARLWCVTSGAVSVSGADGPSAPEQAAVWGFGRVAGLEHPHLWAGLVDLPPEADERTAARLVGVLAGAGGEDQVALRSSGVFVRRLVRAPASEVPAVRSWKPGGTVLVTGGTGGLGRQVARWLARGGADHLLLVSRRGVDAPGADELVDELTDLGARVTVAACDVADRDAVQRLLSEQVPSDAPLTAVIHTAAVLDDGVIDSLSPERMEQVLRVKVGGAVHLYELTRESDLSAFVLFSSFGSTFGLPGLGNYAPGNAALEALAEQWRAEGRPATAVGWGTWATHGIHELEPALATAALEQALERDESSPVIIDIDWERFAVAFHAKRPTRGFELVPEAQAALE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Biosynthetic protein
molecule keywords Polyketide synthase
publication title Modular polyketide synthase contains two reaction chambers that operate asynchronously
doi rcsb
source organism Streptomyces lasalocidi
total genus 147
structure length 510
sequence length 530
chains with identical sequence D
ec nomenclature
pdb deposition date 2021-09-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF08659 KR KR domain
C PF18369 PKS_DE Polyketide synthase dimerisation element domain
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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