7ZJQB

Human tead3 in complex with 1-cyclopentyl-1h-pyrazolo[3,4-b]pyridine-5-carboxylic acid
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
216
structure length
209
Chain Sequence
TIASSRLRLLEYSAFMEVQRDPDTYSKHLFVHIGDPPLEAVDVRQIYDKFPEKKGGLKELYEKGPPNAFFLVKFWADLNSTIQEGPGAFYGVSSQYSSADSMTISVSTKVCSFGKQVVEKVETEYARLENGRFVYRIHRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTSRDSQETLLVIAFVFEVSTSEHGAQHHVYKLVK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Optimization of TEAD P-Site Binding Fragment Hit into In Vivo Active Lead MSC-4106 .
pubmed doi rcsb
molecule tags Transcription
source organism Homo sapiens
molecule keywords Transcriptional enhancer factor TEF-5
total genus 57
structure length 209
sequence length 216
chains with identical sequence C, D
ec nomenclature
pdb deposition date 2022-04-11
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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