9CJ5A

Unphosphorylated human p38 alpha bound to pexmetinib
Total Genus 95
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
348
structure length
334
Chain Sequence
RPTFYRQEKTIWVPERYQNLSPVGSGAYSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEDVYLVTHLMGADLNNIVKCQLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLHTDDYVATRWYRAPEIMLNWMYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Dual-Action Kinase Inhibitors Influence p38 alpha MAP Kinase Dephosphorylation.
pubmed doi rcsb
molecule keywords Mitogen-activated protein kinase 14
molecule tags Transferase
source organism Homo sapiens
total genus 95
structure length 334
sequence length 348
ec nomenclature ec 2.7.11.24: mitogen-activated protein kinase.
pdb deposition date 2024-07-05
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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