9GYOG

Cryoem structure of gs-coupled gpbar with small molecule agonist p395
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
58
structure length
58
Chain Sequence
NTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Deciphering molecular determinants of GPBAR1-Gs protein interactions by HDX-MS and cryo-EM.
pubmed doi rcsb
molecule keywords Isoform Gnas-2 of Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
molecule tags Membrane protein
source organism Homo sapiens
total genus 14
structure length 58
sequence length 58
ec nomenclature
pdb deposition date 2024-10-02
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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