1SI3A

Crystal structure of the paz domain of human eif2c1 in complex with a 9-mer sirna-like duplex
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
126
structure length
120
Chain Sequence
MAQPVIEFMCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Gene regulation/rna
molecule keywords 5'-R(*CP*GP*UP*GP*AP*CP*UP*CP*U)-3'
publication title Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain.
pubmed doi rcsb
source organism Homo sapiens
total genus 26
structure length 120
sequence length 126
ec nomenclature
pdb deposition date 2004-02-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02170 PAZ PAZ domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.260.10 Mainly Beta Beta Complex paz domain paz domain 1si3A00
4NGBA 2XFMA 2L5DA 4NGCA 2L5CA 4OLAA 1T2RA 2FFLA 4W5TA 4NGDA 4KRFA 4Z4EA 4F3TA 4W5RA 3O6EX 5JS1A 1R6ZA 1R4KA 5T7BA 3O7VX 1T2SA 4Z4HA 3MJ0A 1SI3A 4Z4FA 4NH3A 4Z4GA 4W5QA 3O7XA 4NH5A 4NGFA 2QVWA 4W5OA 4Z4CA 1SI2A 4NGGA 1VYNA 4W5NA 4OLBA 3O3IX 4NH6A 4KREA 5JS2A 3QIRA 4Z4IA 5KI6A 4NHAA
chains in the Genus database with same CATH superfamily
4NGBA 2DB9A 3HO1A 2XFMA 3HJFA 2L5DA 3DLBA 4NGCA 2L5CA 4OLAA 1T2RA 2FFLA 4W5TA 4NGDA 4KRFA 4Z4EA 4L1UA 4F3TA 1U04A 4W5RA 3O6EX 5JS1A 1R6ZA 1R4KA 5T7BA 3O7VX 1T2SA 4Z4HA 3DLHA 1SI3A 1Z26A 4Z4FA 3MJ0A 4Z4GA 4NH3A 3HK2A 4L1PA 4W5QA 3O7XA 3HM9A 4NGFA 4NH5A 3HVRA 2QVWA 1Z25A 4W5OA 4Z4CA 1SI2A 4NGGA 1VYNA 4W5NA 4OLBA 3O3IX 4NHAA 4NH6A 5JS2A 3U1UA 3DA5A 3F73A 4KREA 3QIRA 4Z4IA 5KI6A 2BZEA
chains in the Genus database with same CATH topology
4NGBA 2DB9A 3HO1A 2XFMA 3HJFA 2L5DA 3DLBA 4NGCA 2L5CA 4OLAA 1T2RA 2FFLA 4W5TA 4NGDA 4KRFA 4Z4EA 4L1UA 4F3TA 1U04A 4W5RA 3O6EX 5JS1A 1R6ZA 1R4KA 5T7BA 3O7VX 1T2SA 4Z4HA 3DLHA 1SI3A 1Z26A 4Z4FA 3MJ0A 4Z4GA 4NH3A 3HK2A 4L1PA 4W5QA 3O7XA 3HM9A 4NGFA 4NH5A 3HVRA 2QVWA 1Z25A 4W5OA 4Z4CA 1SI2A 4NGGA 1VYNA 4W5NA 4OLBA 3O3IX 4NHAA 4NH6A 5JS2A 3U1UA 3DA5A 3F73A 4KREA 3QIRA 4Z4IA 5KI6A 2BZEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NGB A;  2XFM A;  2L5D A;  4NGC A;  2L5C A;  4OLA A;  1T2R A;  2FFL A;  4W5T A;  4NGD A;  4KRF A;  4Z4E A;  4F3T A;  4W5R A;  3O6E X;  5JS1 A;  1R6Z A;  1R4K A;  5T7B A;  3O7V X;  1T2S A;  4Z4H A;  3MJ0 A;  1SI3 A;  4Z4F A;  4NH3 A;  4Z4G A;  4W5Q A;  3O7X A;  4NH5 A;  4NGF A;  2QVW A;  4W5O A;  4Z4C A;  1SI2 A;  4NGG A;  1VYN A;  4W5N A;  4OLB A;  3O3I X;  4NH6 A;  4KRE A;  5JS2 A;  3QIR A;  4Z4I A;  5KI6 A;  4NHA A; 
#chains in the Genus database with same CATH topology
 4NGB A;  2DB9 A;  3HO1 A;  2XFM A;  3HJF A;  2L5D A;  3DLB A;  4NGC A;  2L5C A;  4OLA A;  1T2R A;  2FFL A;  4W5T A;  4NGD A;  4KRF A;  4Z4E A;  4L1U A;  4F3T A;  1U04 A;  4W5R A;  3O6E X;  5JS1 A;  1R6Z A;  1R4K A;  5T7B A;  3O7V X;  1T2S A;  4Z4H A;  3DLH A;  1SI3 A;  1Z26 A;  4Z4F A;  3MJ0 A;  4Z4G A;  4NH3 A;  3HK2 A;  4L1P A;  4W5Q A;  3O7X A;  3HM9 A;  4NGF A;  4NH5 A;  3HVR A;  2QVW A;  1Z25 A;  4W5O A;  4Z4C A;  1SI2 A;  4NGG A;  1VYN A;  4W5N A;  4OLB A;  3O3I X;  4NHA A;  4NH6 A;  5JS2 A;  3U1U A;  3DA5 A;  3F73 A;  4KRE A;  3QIR A;  4Z4I A;  5KI6 A;  2BZE A; 
#chains in the Genus database with same CATH homology
 4NGB A;  2DB9 A;  3HO1 A;  2XFM A;  3HJF A;  2L5D A;  3DLB A;  4NGC A;  2L5C A;  4OLA A;  1T2R A;  2FFL A;  4W5T A;  4NGD A;  4KRF A;  4Z4E A;  4L1U A;  4F3T A;  1U04 A;  4W5R A;  3O6E X;  5JS1 A;  1R6Z A;  1R4K A;  5T7B A;  3O7V X;  1T2S A;  4Z4H A;  3DLH A;  1SI3 A;  1Z26 A;  4Z4F A;  3MJ0 A;  4Z4G A;  4NH3 A;  3HK2 A;  4L1P A;  4W5Q A;  3O7X A;  3HM9 A;  4NGF A;  4NH5 A;  3HVR A;  2QVW A;  1Z25 A;  4W5O A;  4Z4C A;  1SI2 A;  4NGG A;  1VYN A;  4W5N A;  4OLB A;  3O3I X;  4NHA A;  4NH6 A;  5JS2 A;  3U1U A;  3DA5 A;  3F73 A;  4KRE A;  3QIR A;  4Z4I A;  5KI6 A;  2BZE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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