1YHMA

Structure of the complex of trypanosoma cruzi farnesyl disphosphate synthase with alendronate, isopentenyl diphosphate and mg+2
Total Genus 136
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
136
sequence length
362
structure length
362
Chain Sequence
MASMERFLSVYDEVQAFLLDQLQSKYEIDPNRARYLRIMMDTTCLGGKYFRGMTVVNVAEGFLAVTQHDEATKERILHDACVGGWMIEFLQAHYLVEDDIMDGSVMRRGKPCWYRFPGVTTQCAINDGIILKSWTQIMAWHYFADRPFLKDLLCLFQKVDYATAVGQMYDVTSMCDSNKLDPEVAQPMTTDFAEFTPAIYKRIVKYKTTFYTYLLPLVMGLFVSEAAASVEMNLVERVAHLIGEYFQVQDDVMDCFTPPEQLGKVGTDIEDAKCSWLAVTFLGKANAAQVAEFKANYGDKDPAKVAVVKRLYSEANLQADFAAYEAEVVREVESLIEQLKVKSPTFAESVAVVWEKTHKRKK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Transferase
molecule keywords farnesyl pyrophosphate synthase
publication title Structure and mechanism of the farnesyl diphosphate synthase from Trypanosoma cruzi: Implications for drug design.
pubmed doi rcsb
source organism Trypanosoma cruzi
total genus 136
structure length 362
sequence length 362
chains with identical sequence B, C
ec nomenclature ec 2.5.1.10: (2E,6E)-farnesyl diphosphate synthase.
pdb deposition date 2005-01-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 1yhmA00
5ERNA 3PH7A 5IM1A 4F6XA 1VG4A 1PS1A 4HD1A 2ZCRA 5JV0F 2E94A 5IL3A 3P5PA 4P0VA 2ZCOA 3KRPB 4E9ZA 4RXCA 2ZCSA 3Q30A 2Q58A 1YYRA 5ILIA 4LOBA 5EROA 3S9VA 3KRPA 2OGDA 5EASA 3VJEA 1YHMA 2ZEVA 3LGKA 4XQSF 3VJBA 5B0KA 2PS7A 4KQ5A 3AQBB 3N45F 2F8CF 3N6KF 5IMPA 3B7LA 3M02A 2QISA 3WCEA 4KVYA 3WEIA 4JVJF 4ZQ8A 1YQ7A 2E95A 1N24A 3PDEA 3QQVA 1VG2A 4NKFA 3WCMA 4P0WA 3MZVA 1YHLA 3KRCB 2Z4XA 3TFNA 3V66A 4LZ0A 4FP4A 4KK2A 4P0XA 3N5HF 2J1PA 3WEHA 3ZCDA 4OMGA 5IN8A 5C05A 4RYPA 4JZBA 5I1UA 3RYWA 3KROB 2Z4YA 3N49F 3IBAA 3N1WF 3G4FA 3SDRA 1N1ZA 4PVXF 5DIQF 3KROA 3ACWA 4NUAA 1WMWA 2ZY1A 2Z52A 4OGUA 1YHKA 2E8UA 3BNXA 5B02A 4KFAA 3APZA 4LXWA 3WJNA 3SAEA 1FPSA 3LG5A 3TFPA 2Z4ZA 4GP2A 3RMGA 3PYBA 3G4DA 2E8VA 4N9UA 2PS8A 2ONHA 3ZL6A 3ICZA 4KQSA 1HXCA 3M00A 4DWBA 3NPRA 5A0IA 3WCLA 3WSAA 4LPHF 3WCGA 2H8OA 4LA6A 3OABA 3ZOUA 4KPJA 3ZMBA 3VJAA 1WKZA 3RBMA 3DYFA 4OMHA 3N1VF 4LFEA 1RQIA 3WC9A 3SDVA 4JXNA 3S4JA 5B0IA 1YYQA 4KQUA 4KKMA 4NFKF 1HM7A 1YYTA 4XQRF 5ILYA 5EAUA 3P41A 5B01A 3N46F 2Z4VA 1UBWA 1YJ4A 3WJKA 4F62A 3IPIA 4L2XF 2PS5A 5E8KA 2Z7IA 3AE0A 5IK6A 2ZCQA 2E93A 4DI5A 4Q23A 5DJPF 5AYPA 5DJVF 2AELA 5CG6A 1JFAA 2AZKA 2J5CA 1RTRA 4GA3A 3V1XA 4MC3A 3Q1OA 5B0MA 2OPMA 3ACXA 4RXAA 3WJOA 3EFQA 3V1VA 4MC0A 4XQTF 4LTVA 3M0GA 4NFIF 5JV1F 3WEKA 2AZLA 4LZCA 3LSNA 3LVSA 3LJIA 1WL2A 3WEJA 3KRCA 5JUZF 4LUUA 5DJRF 3LOMA 3N3DA 5DHIA 4DEMF 3Q2QA 3NPKA 5IKHA 3RYEA 2F9KF 4JXYA 5H9DA 5IMIA 5ILDA 3N5JF 3EZ3A 4KPDA 2OPNA 4UMJA 4KUXA 5A0JA 5AFXA 5E8LA 5A0KA 3PYAA 2E4OA 3CP6A 1DI1A 3CC9A 4OKMA 4LZ3A 2PS4A 1HM4A 5IK0A 1HX9A 3ID0A 5ILKA 4MC8A 3WCBA 4DWGA 4PVYF 5IKAA 2E91A 2Z78A 1V4JA 2E92A 3WCFA 4RXEA 2VF6A 3ACYA 4RNQA 3WCDA 4LFVF 3LDWA 3Q2ZA 3OACB 1N20A 4H5DF 4E9UA 1VG7A 3WEGA 3TFVA 1UBYA 3AQ0A 3QKCA 1VG6A 5IVGA 2E90A 3LLWA 5ILZA 3ICMA 4LFGA 1V4EA 3KRFB 3N0GA 5E8HA 4H5EF 5JV2F 1HXAA 2FORA 2EWGA 3P8RA 3TS7A 2J1OA 3NRIA 2OA6A 1EZFA 4H5CF 1ZW5A 2O1OA 3KBKA 3WCCA 4QPFA 3PKOA 3LZ9A 3SDUA 2AEKA 2I19A 5DHKA 2ONGA 5DZ2A 4LTZA 5AHUB 1WL1A 5B03A 1HXGA 3ICNA 3LGZB 3ADZA 1YV5A 3KRAB 3M01A 4NFJF 3ZMCA 1UBVA 2F92F 2FTZA 3KRAA 3WCIA 1KIYA 2Q80A 3VJ8A 5AELA 3DYHA 5ER8A 3DYGA 5HN7A 2E8WA 5IK9A 2F94F 5HN9A 3UCAA 5EATA 2RAHA 5JA0F 4KWDA 3P5RA 4EA1A 2F89F 1YYSA 1WL0A 2P1CA 3KB9A 3P8LA 4LIXA 3WCJA 4N1ZF 1RQJA 2DH4A 5IMNA 1WY0A 4GP1A 3LEEA 4KVDA 3EGTA 4LLSA 5ILHA 1N1BA 4NKEA 1WL3A 1N21A 5B0JA 4RXDA 3MAVA 4GAXA 4DZWA 4EA0A 2AETA 3ICKA 4OKZA 5DGNF 3VJCA 5ERMA 1KIZA 1N23A 5DW7A 4WK5A 4QXSF 5IL8A 1V4KA 1VG3A 4EA2A 3WSBA 5B00A 3NF2A 4DHDA 2ZEUA 3OYRA 3WCHA 3WE9A 5HN8A 3VJDA 1V4IA 4K10A 4LPGF 5DGMF 3SDTA 1DGPA 2AZJA 3ASXA 3M9UA 2F8ZF 3BNYA 5CG5A 3N0FA 1N22A 4KVIA 4E1EA 3SDQA 3N3LF 1YYUA 2Z50A 4LLTA 3LMDA 3AQCB 5ILJA 3W7FA 4JYXA 4DXJA 1UBXA 2Z4WA 3OACA 3WCAA 2Q9YA 1JFGA 2Z7HA 4KVWA 5HNAA 5KSXF 3LK5A 3OABB 4JZXA 2PS6A 3KRFA 1V4HA 4LA5A 4F6VA 2E8XA 3TC1A 2F7MF 5DGSF 4FJQA 2Q9ZA 3WEFA 3CKEA 2E8TA 4NG6A 5B0LA 3VJ9A
chains in the Genus database with same CATH superfamily
5ERNA 3PH7A 5IM1A 4F6XA 1VG4A 1PS1A 4HD1A 2ZCRA 5JV0F 2E94A 5IL3A 3P5PA 4P0VA 2ZCOA 3KRPB 4E9ZA 4RXCA 2ZCSA 3Q30A 2Q58A 1YYRA 5ILIA 4LOBA 5EROA 3S9VA 3KRPA 2OGDA 5EASA 3VJEA 1YHMA 2ZEVA 3LGKA 4XQSF 3VJBA 5B0KA 2PS7A 4KQ5A 3AQBB 3N45F 2F8CF 3N6KF 5IMPA 3B7LA 3M02A 2QISA 3WCEA 4KVYA 3WEIA 4JVJF 4ZQ8A 1YQ7A 2E95A 1N24A 3PDEA 3QQVA 1VG2A 4NKFA 3WCMA 4P0WA 3MZVA 1YHLA 3KRCB 2Z4XA 3TFNA 3V66A 4LZ0A 4FP4A 4KK2A 4P0XA 3N5HF 2J1PA 3WEHA 3ZCDA 4OMGA 5IN8A 5C05A 4RYPA 4JZBA 5I1UA 3RYWA 3KROB 2Z4YA 3N49F 3IBAA 3N1WF 3G4FA 3SDRA 1N1ZA 4PVXF 5DIQF 3KROA 3ACWA 4NUAA 1WMWA 2ZY1A 2Z52A 4OGUA 1YHKA 2E8UA 3BNXA 5B02A 4KFAA 3APZA 4LXWA 3WJNA 3SAEA 1FPSA 3LG5A 3TFPA 2Z4ZA 4GP2A 3RMGA 3PYBA 3G4DA 2E8VA 4N9UA 2PS8A 2ONHA 3ZL6A 3ICZA 4KQSA 1HXCA 3M00A 4DWBA 3NPRA 5A0IA 3WCLA 3WSAA 4LPHF 3WCGA 2H8OA 4LA6A 3OABA 3ZOUA 4KPJA 3ZMBA 3VJAA 1WKZA 3RBMA 3DYFA 4OMHA 3N1VF 4LFEA 1RQIA 3WC9A 3SDVA 4JXNA 3S4JA 5B0IA 1YYQA 4KQUA 4KKMA 4NFKF 1HM7A 1YYTA 4XQRF 5ILYA 5EAUA 3P41A 5B01A 3N46F 2Z4VA 1UBWA 1YJ4A 3WJKA 4F62A 3IPIA 4L2XF 2PS5A 5E8KA 2Z7IA 3AE0A 5IK6A 2ZCQA 2E93A 4DI5A 4Q23A 5DJPF 5AYPA 5DJVF 2AELA 5CG6A 1JFAA 2AZKA 2J5CA 1RTRA 4GA3A 3V1XA 4MC3A 3Q1OA 5B0MA 2OPMA 3ACXA 4RXAA 3WJOA 3EFQA 3V1VA 4MC0A 4XQTF 4LTVA 3M0GA 4NFIF 5JV1F 3WEKA 2AZLA 4LZCA 3LSNA 3LVSA 3LJIA 1WL2A 3WEJA 3KRCA 5JUZF 4LUUA 5DJRF 3LOMA 3N3DA 5DHIA 4DEMF 3Q2QA 3NPKA 5IKHA 3RYEA 2F9KF 4JXYA 5H9DA 5IMIA 5ILDA 3N5JF 3EZ3A 4KPDA 2OPNA 4UMJA 4KUXA 5A0JA 5AFXA 5E8LA 5A0KA 3PYAA 2E4OA 3CP6A 1DI1A 3CC9A 4OKMA 4LZ3A 2PS4A 1HM4A 5IK0A 1HX9A 3ID0A 5ILKA 4MC8A 3WCBA 4DWGA 4PVYF 5IKAA 2E91A 2Z78A 1V4JA 2E92A 3WCFA 4RXEA 2VF6A 3ACYA 4RNQA 3WCDA 4LFVF 3LDWA 3Q2ZA 3OACB 1N20A 4H5DF 4E9UA 1VG7A 3WEGA 3TFVA 1UBYA 3AQ0A 3QKCA 1VG6A 5IVGA 2E90A 3LLWA 5ILZA 3ICMA 4LFGA 1V4EA 3KRFB 3N0GA 5E8HA 4H5EF 5JV2F 1HXAA 2FORA 2EWGA 3P8RA 3TS7A 2J1OA 3NRIA 2OA6A 1EZFA 4H5CF 1ZW5A 2O1OA 3KBKA 3WCCA 4QPFA 3PKOA 3LZ9A 3SDUA 2AEKA 2I19A 5DHKA 2ONGA 5DZ2A 4LTZA 5AHUB 1WL1A 5B03A 1HXGA 3ICNA 3LGZB 3ADZA 1YV5A 3KRAB 3M01A 4NFJF 3ZMCA 1UBVA 2F92F 2FTZA 3KRAA 3WCIA 1KIYA 2Q80A 3VJ8A 5AELA 3DYHA 5ER8A 3DYGA 5HN7A 2E8WA 5IK9A 2F94F 5HN9A 3UCAA 5EATA 2RAHA 5JA0F 4KWDA 3P5RA 4EA1A 2F89F 1YYSA 1WL0A 2P1CA 3KB9A 3P8LA 4LIXA 3WCJA 4N1ZF 1RQJA 2DH4A 5IMNA 1WY0A 4GP1A 3LEEA 4KVDA 3EGTA 4LLSA 5ILHA 1N1BA 4NKEA 1WL3A 1N21A 5B0JA 4RXDA 3MAVA 4GAXA 4DZWA 4EA0A 2AETA 3ICKA 4OKZA 5DGNF 3VJCA 5ERMA 1KIZA 1N23A 5DW7A 4WK5A 4QXSF 5IL8A 1V4KA 1VG3A 4EA2A 3WSBA 5B00A 3NF2A 4DHDA 2ZEUA 3OYRA 3WCHA 3WE9A 5HN8A 3VJDA 1V4IA 4K10A 4LPGF 5DGMF 3SDTA 1DGPA 2AZJA 3ASXA 3M9UA 2F8ZF 3BNYA 5CG5A 3N0FA 1N22A 4KVIA 4E1EA 3SDQA 3N3LF 1YYUA 2Z50A 4LLTA 3LMDA 3AQCB 5ILJA 3W7FA 4JYXA 4DXJA 1UBXA 2Z4WA 3OACA 3WCAA 2Q9YA 1JFGA 2Z7HA 4KVWA 5HNAA 5KSXF 3LK5A 3OABB 4JZXA 2PS6A 3KRFA 1V4HA 4LA5A 4F6VA 2E8XA 3TC1A 2F7MF 5DGSF 4FJQA 2Q9ZA 3WEFA 3CKEA 2E8TA 4NG6A 5B0LA 3VJ9A
chains in the Genus database with same CATH topology
5ERNA 3PH7A 5IM1A 4F6XA 1VG4A 1PS1A 4HD1A 2ZCRA 5JV0F 2E94A 5IL3A 3P5PA 4P0VA 2ZCOA 3KRPB 4E9ZA 4RXCA 2ZCSA 3Q30A 2Q58A 1YYRA 5ILIA 4LOBA 5EROA 3S9VA 3KRPA 2OGDA 5EASA 3VJEA 1YHMA 2ZEVA 3LGKA 4XQSF 3VJBA 5B0KA 2PS7A 4KQ5A 3AQBB 3N45F 2F8CF 3N6KF 5IMPA 3B7LA 3M02A 2QISA 3WCEA 4KVYA 3WEIA 4JVJF 4ZQ8A 1YQ7A 2E95A 1N24A 3PDEA 3QQVA 1VG2A 4NKFA 3WCMA 4P0WA 3MZVA 1YHLA 3KRCB 2Z4XA 3TFNA 3V66A 4LZ0A 4FP4A 4KK2A 4P0XA 3N5HF 2J1PA 3WEHA 3ZCDA 4OMGA 5IN8A 5C05A 4RYPA 4JZBA 5I1UA 3RYWA 3KROB 2Z4YA 3N49F 3IBAA 3N1WF 3G4FA 3SDRA 1N1ZA 4PVXF 5DIQF 3KROA 3ACWA 4NUAA 1WMWA 2ZY1A 2Z52A 4OGUA 1YHKA 2E8UA 3BNXA 5B02A 4KFAA 3APZA 4LXWA 3WJNA 3SAEA 1FPSA 3LG5A 3TFPA 2Z4ZA 4GP2A 3RMGA 3PYBA 3G4DA 2E8VA 4N9UA 2PS8A 2ONHA 3ZL6A 3ICZA 4KQSA 1HXCA 3M00A 4DWBA 3NPRA 5A0IA 3WCLA 3WSAA 4LPHF 3WCGA 2H8OA 4LA6A 3OABA 3ZOUA 4KPJA 3ZMBA 3VJAA 1WKZA 3RBMA 3DYFA 4OMHA 3N1VF 4LFEA 1RQIA 3WC9A 3SDVA 4JXNA 3S4JA 5B0IA 1YYQA 4KQUA 4KKMA 4NFKF 1HM7A 1YYTA 4XQRF 5ILYA 5EAUA 3P41A 5B01A 3N46F 2Z4VA 1UBWA 1YJ4A 3WJKA 4F62A 3IPIA 4L2XF 2PS5A 5E8KA 2Z7IA 3AE0A 5IK6A 2ZCQA 2E93A 4DI5A 4Q23A 5DJPF 5AYPA 5DJVF 2AELA 5CG6A 1JFAA 2AZKA 2J5CA 1RTRA 4GA3A 3V1XA 4MC3A 3Q1OA 5B0MA 2OPMA 3ACXA 4RXAA 3WJOA 3EFQA 3V1VA 4MC0A 4XQTF 4LTVA 3M0GA 4NFIF 5JV1F 3WEKA 2AZLA 4LZCA 3LSNA 3LVSA 3LJIA 1WL2A 3WEJA 3KRCA 5JUZF 4LUUA 5DJRF 3LOMA 3N3DA 5DHIA 4DEMF 3Q2QA 3NPKA 5IKHA 3RYEA 2F9KF 4JXYA 5H9DA 5IMIA 5ILDA 3N5JF 3EZ3A 4KPDA 2OPNA 4UMJA 4KUXA 5A0JA 5AFXA 5E8LA 5A0KA 3PYAA 2E4OA 3CP6A 1DI1A 3CC9A 4OKMA 4LZ3A 2PS4A 1HM4A 5IK0A 1HX9A 3ID0A 5ILKA 4MC8A 3WCBA 4DWGA 4PVYF 5IKAA 2E91A 2Z78A 1V4JA 2E92A 3WCFA 4RXEA 2VF6A 3ACYA 4RNQA 3WCDA 4LFVF 3LDWA 3Q2ZA 3OACB 1N20A 4H5DF 4E9UA 1VG7A 3WEGA 3TFVA 1UBYA 3AQ0A 3QKCA 1VG6A 5IVGA 2E90A 3LLWA 5ILZA 3ICMA 4LFGA 1V4EA 3KRFB 3N0GA 5E8HA 4H5EF 5JV2F 1HXAA 2FORA 2EWGA 3P8RA 3TS7A 2J1OA 3NRIA 2OA6A 1EZFA 4H5CF 1ZW5A 2O1OA 3KBKA 3WCCA 4QPFA 3PKOA 3LZ9A 3SDUA 2AEKA 2I19A 5DHKA 2ONGA 5DZ2A 4LTZA 5AHUB 1WL1A 5B03A 1HXGA 3ICNA 3LGZB 3ADZA 1YV5A 3KRAB 3M01A 4NFJF 3ZMCA 1UBVA 2F92F 2FTZA 3KRAA 3WCIA 1KIYA 2Q80A 3VJ8A 5AELA 3DYHA 5ER8A 3DYGA 5HN7A 2E8WA 5IK9A 2F94F 5HN9A 3UCAA 5EATA 2RAHA 5JA0F 4KWDA 3P5RA 4EA1A 2F89F 1YYSA 1WL0A 2P1CA 3KB9A 3P8LA 4LIXA 3WCJA 4N1ZF 1RQJA 2DH4A 5IMNA 1WY0A 4GP1A 3LEEA 4KVDA 3EGTA 4LLSA 5ILHA 1N1BA 4NKEA 1WL3A 1N21A 5B0JA 4RXDA 3MAVA 4GAXA 4DZWA 4EA0A 2AETA 3ICKA 4OKZA 5DGNF 3VJCA 5ERMA 1KIZA 1N23A 5DW7A 4WK5A 4QXSF 5IL8A 1V4KA 1VG3A 4EA2A 3WSBA 5B00A 3NF2A 4DHDA 2ZEUA 3OYRA 3WCHA 3WE9A 5HN8A 3VJDA 1V4IA 4K10A 4LPGF 5DGMF 3SDTA 1DGPA 2AZJA 3ASXA 3M9UA 2F8ZF 3BNYA 5CG5A 3N0FA 1N22A 4KVIA 4E1EA 3SDQA 3N3LF 1YYUA 2Z50A 4LLTA 3LMDA 3AQCB 5ILJA 3W7FA 4JYXA 4DXJA 1UBXA 2Z4WA 3OACA 3WCAA 2Q9YA 1JFGA 2Z7HA 4KVWA 5HNAA 5KSXF 3LK5A 3OABB 4JZXA 2PS6A 3KRFA 1V4HA 4LA5A 4F6VA 2E8XA 3TC1A 2F7MF 5DGSF 4FJQA 2Q9ZA 3WEFA 3CKEA 2E8TA 4NG6A 5B0LA 3VJ9A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 5ERN A;  3PH7 A;  5IM1 A;  4F6X A;  1VG4 A;  1PS1 A;  4HD1 A;  2ZCR A;  5JV0 F;  2E94 A;  5IL3 A;  3P5P A;  4P0V A;  2ZCO A;  3KRP B;  4E9Z A;  4RXC A;  2ZCS A;  3Q30 A;  2Q58 A;  1YYR A;  5ILI A;  4LOB A;  5ERO A;  3S9V A;  3KRP A;  2OGD A;  5EAS A;  3VJE A;  1YHM A;  2ZEV A;  3LGK A;  4XQS F;  3VJB A;  5B0K A;  2PS7 A;  4KQ5 A;  3AQB B;  3N45 F;  2F8C F;  3N6K F;  5IMP A;  3B7L A;  3M02 A;  2QIS A;  3WCE A;  4KVY A;  3WEI A;  4JVJ F;  4ZQ8 A;  1YQ7 A;  2E95 A;  1N24 A;  3PDE A;  3QQV A;  1VG2 A;  4NKF A;  3WCM A;  4P0W A;  3MZV A;  1YHL A;  3KRC B;  2Z4X A;  3TFN A;  3V66 A;  4LZ0 A;  4FP4 A;  4KK2 A;  4P0X A;  3N5H F;  2J1P A;  3WEH A;  3ZCD A;  4OMG A;  5IN8 A;  5C05 A;  4RYP A;  4JZB A;  5I1U A;  3RYW A;  3KRO B;  2Z4Y A;  3N49 F;  3IBA A;  3N1W F;  3G4F A;  3SDR A;  1N1Z A;  4PVX F;  5DIQ F;  3KRO A;  3ACW A;  4NUA A;  1WMW A;  2ZY1 A;  2Z52 A;  4OGU A;  1YHK A;  2E8U A;  3BNX A;  5B02 A;  4KFA A;  3APZ A;  4LXW A;  3WJN A;  3SAE A;  1FPS A;  3LG5 A;  3TFP A;  2Z4Z A;  4GP2 A;  3RMG A;  3PYB A;  3G4D A;  2E8V A;  4N9U A;  2PS8 A;  2ONH A;  3ZL6 A;  3ICZ A;  4KQS A;  1HXC A;  3M00 A;  4DWB A;  3NPR A;  5A0I A;  3WCL A;  3WSA A;  4LPH F;  3WCG A;  2H8O A;  4LA6 A;  3OAB A;  3ZOU A;  4KPJ A;  3ZMB A;  3VJA A;  1WKZ A;  3RBM A;  3DYF A;  4OMH A;  3N1V F;  4LFE A;  1RQI A;  3WC9 A;  3SDV A;  4JXN A;  3S4J A;  5B0I A;  1YYQ A;  4KQU A;  4KKM A;  4NFK F;  1HM7 A;  1YYT A;  4XQR F;  5ILY A;  5EAU A;  3P41 A;  5B01 A;  3N46 F;  2Z4V A;  1UBW A;  1YJ4 A;  3WJK A;  4F62 A;  3IPI A;  4L2X F;  2PS5 A;  5E8K A;  2Z7I A;  3AE0 A;  5IK6 A;  2ZCQ A;  2E93 A;  4DI5 A;  4Q23 A;  5DJP F;  5AYP A;  5DJV F;  2AEL A;  5CG6 A;  1JFA A;  2AZK A;  2J5C A;  1RTR A;  4GA3 A;  3V1X A;  4MC3 A;  3Q1O A;  5B0M A;  2OPM A;  3ACX A;  4RXA A;  3WJO A;  3EFQ A;  3V1V A;  4MC0 A;  4XQT F;  4LTV A;  3M0G A;  4NFI F;  5JV1 F;  3WEK A;  2AZL A;  4LZC A;  3LSN A;  3LVS A;  3LJI A;  1WL2 A;  3WEJ A;  3KRC A;  5JUZ F;  4LUU A;  5DJR F;  3LOM A;  3N3D A;  5DHI A;  4DEM F;  3Q2Q A;  3NPK A;  5IKH A;  3RYE A;  2F9K F;  4JXY A;  5H9D A;  5IMI A;  5ILD A;  3N5J F;  3EZ3 A;  4KPD A;  2OPN A;  4UMJ A;  4KUX A;  5A0J A;  5AFX A;  5E8L A;  5A0K A;  3PYA A;  2E4O A;  3CP6 A;  1DI1 A;  3CC9 A;  4OKM A;  4LZ3 A;  2PS4 A;  1HM4 A;  5IK0 A;  1HX9 A;  3ID0 A;  5ILK A;  4MC8 A;  3WCB A;  4DWG A;  4PVY F;  5IKA A;  2E91 A;  2Z78 A;  1V4J A;  2E92 A;  3WCF A;  4RXE A;  2VF6 A;  3ACY A;  4RNQ A;  3WCD A;  4LFV F;  3LDW A;  3Q2Z A;  3OAC B;  1N20 A;  4H5D F;  4E9U A;  1VG7 A;  3WEG A;  3TFV A;  1UBY A;  3AQ0 A;  3QKC A;  1VG6 A;  5IVG A;  2E90 A;  3LLW A;  5ILZ A;  3ICM A;  4LFG A;  1V4E A;  3KRF B;  3N0G A;  5E8H A;  4H5E F;  5JV2 F;  1HXA A;  2FOR A;  2EWG A;  3P8R A;  3TS7 A;  2J1O A;  3NRI A;  2OA6 A;  1EZF A;  4H5C F;  1ZW5 A;  2O1O A;  3KBK A;  3WCC A;  4QPF A;  3PKO A;  3LZ9 A;  3SDU A;  2AEK A;  2I19 A;  5DHK A;  2ONG A;  5DZ2 A;  4LTZ A;  5AHU B;  1WL1 A;  5B03 A;  1HXG A;  3ICN A;  3LGZ B;  3ADZ A;  1YV5 A;  3KRA B;  3M01 A;  4NFJ F;  3ZMC A;  1UBV A;  2F92 F;  2FTZ A;  3KRA A;  3WCI A;  1KIY A;  2Q80 A;  3VJ8 A;  5AEL A;  3DYH A;  5ER8 A;  3DYG A;  5HN7 A;  2E8W A;  5IK9 A;  2F94 F;  5HN9 A;  3UCA A;  5EAT A;  2RAH A;  5JA0 F;  4KWD A;  3P5R A;  4EA1 A;  2F89 F;  1YYS A;  1WL0 A;  2P1C A;  3KB9 A;  3P8L A;  4LIX A;  3WCJ A;  4N1Z F;  1RQJ A;  2DH4 A;  5IMN A;  1WY0 A;  4GP1 A;  3LEE A;  4KVD A;  3EGT A;  4LLS A;  5ILH A;  1N1B A;  4NKE A;  1WL3 A;  1N21 A;  5B0J A;  4RXD A;  3MAV A;  4GAX A;  4DZW A;  4EA0 A;  2AET A;  3ICK A;  4OKZ A;  5DGN F;  3VJC A;  5ERM A;  1KIZ A;  1N23 A;  5DW7 A;  4WK5 A;  4QXS F;  5IL8 A;  1V4K A;  1VG3 A;  4EA2 A;  3WSB A;  5B00 A;  3NF2 A;  4DHD A;  2ZEU A;  3OYR A;  3WCH A;  3WE9 A;  5HN8 A;  3VJD A;  1V4I A;  4K10 A;  4LPG F;  5DGM F;  3SDT A;  1DGP A;  2AZJ A;  3ASX A;  3M9U A;  2F8Z F;  3BNY A;  5CG5 A;  3N0F A;  1N22 A;  4KVI A;  4E1E A;  3SDQ A;  3N3L F;  1YYU A;  2Z50 A;  4LLT A;  3LMD A;  3AQC B;  5ILJ A;  3W7F A;  4JYX A;  4DXJ A;  1UBX A;  2Z4W A;  3OAC A;  3WCA A;  2Q9Y A;  1JFG A;  2Z7H A;  4KVW A;  5HNA A;  5KSX F;  3LK5 A;  3OAB B;  4JZX A;  2PS6 A;  3KRF A;  1V4H A;  4LA5 A;  4F6V A;  2E8X A;  3TC1 A;  2F7M F;  5DGS F;  4FJQ A;  2Q9Z A;  3WEF A;  3CKE A;  2E8T A;  4NG6 A;  5B0L A;  3VJ9 A; 
#chains in the Genus database with same CATH topology
 5ERN A;  3PH7 A;  5IM1 A;  4F6X A;  1VG4 A;  1PS1 A;  4HD1 A;  2ZCR A;  5JV0 F;  2E94 A;  5IL3 A;  3P5P A;  4P0V A;  2ZCO A;  3KRP B;  4E9Z A;  4RXC A;  2ZCS A;  3Q30 A;  2Q58 A;  1YYR A;  5ILI A;  4LOB A;  5ERO A;  3S9V A;  3KRP A;  2OGD A;  5EAS A;  3VJE A;  1YHM A;  2ZEV A;  3LGK A;  4XQS F;  3VJB A;  5B0K A;  2PS7 A;  4KQ5 A;  3AQB B;  3N45 F;  2F8C F;  3N6K F;  5IMP A;  3B7L A;  3M02 A;  2QIS A;  3WCE A;  4KVY A;  3WEI A;  4JVJ F;  4ZQ8 A;  1YQ7 A;  2E95 A;  1N24 A;  3PDE A;  3QQV A;  1VG2 A;  4NKF A;  3WCM A;  4P0W A;  3MZV A;  1YHL A;  3KRC B;  2Z4X A;  3TFN A;  3V66 A;  4LZ0 A;  4FP4 A;  4KK2 A;  4P0X A;  3N5H F;  2J1P A;  3WEH A;  3ZCD A;  4OMG A;  5IN8 A;  5C05 A;  4RYP A;  4JZB A;  5I1U A;  3RYW A;  3KRO B;  2Z4Y A;  3N49 F;  3IBA A;  3N1W F;  3G4F A;  3SDR A;  1N1Z A;  4PVX F;  5DIQ F;  3KRO A;  3ACW A;  4NUA A;  1WMW A;  2ZY1 A;  2Z52 A;  4OGU A;  1YHK A;  2E8U A;  3BNX A;  5B02 A;  4KFA A;  3APZ A;  4LXW A;  3WJN A;  3SAE A;  1FPS A;  3LG5 A;  3TFP A;  2Z4Z A;  4GP2 A;  3RMG A;  3PYB A;  3G4D A;  2E8V A;  4N9U A;  2PS8 A;  2ONH A;  3ZL6 A;  3ICZ A;  4KQS A;  1HXC A;  3M00 A;  4DWB A;  3NPR A;  5A0I A;  3WCL A;  3WSA A;  4LPH F;  3WCG A;  2H8O A;  4LA6 A;  3OAB A;  3ZOU A;  4KPJ A;  3ZMB A;  3VJA A;  1WKZ A;  3RBM A;  3DYF A;  4OMH A;  3N1V F;  4LFE A;  1RQI A;  3WC9 A;  3SDV A;  4JXN A;  3S4J A;  5B0I A;  1YYQ A;  4KQU A;  4KKM A;  4NFK F;  1HM7 A;  1YYT A;  4XQR F;  5ILY A;  5EAU A;  3P41 A;  5B01 A;  3N46 F;  2Z4V A;  1UBW A;  1YJ4 A;  3WJK A;  4F62 A;  3IPI A;  4L2X F;  2PS5 A;  5E8K A;  2Z7I A;  3AE0 A;  5IK6 A;  2ZCQ A;  2E93 A;  4DI5 A;  4Q23 A;  5DJP F;  5AYP A;  5DJV F;  2AEL A;  5CG6 A;  1JFA A;  2AZK A;  2J5C A;  1RTR A;  4GA3 A;  3V1X A;  4MC3 A;  3Q1O A;  5B0M A;  2OPM A;  3ACX A;  4RXA A;  3WJO A;  3EFQ A;  3V1V A;  4MC0 A;  4XQT F;  4LTV A;  3M0G A;  4NFI F;  5JV1 F;  3WEK A;  2AZL A;  4LZC A;  3LSN A;  3LVS A;  3LJI A;  1WL2 A;  3WEJ A;  3KRC A;  5JUZ F;  4LUU A;  5DJR F;  3LOM A;  3N3D A;  5DHI A;  4DEM F;  3Q2Q A;  3NPK A;  5IKH A;  3RYE A;  2F9K F;  4JXY A;  5H9D A;  5IMI A;  5ILD A;  3N5J F;  3EZ3 A;  4KPD A;  2OPN A;  4UMJ A;  4KUX A;  5A0J A;  5AFX A;  5E8L A;  5A0K A;  3PYA A;  2E4O A;  3CP6 A;  1DI1 A;  3CC9 A;  4OKM A;  4LZ3 A;  2PS4 A;  1HM4 A;  5IK0 A;  1HX9 A;  3ID0 A;  5ILK A;  4MC8 A;  3WCB A;  4DWG A;  4PVY F;  5IKA A;  2E91 A;  2Z78 A;  1V4J A;  2E92 A;  3WCF A;  4RXE A;  2VF6 A;  3ACY A;  4RNQ A;  3WCD A;  4LFV F;  3LDW A;  3Q2Z A;  3OAC B;  1N20 A;  4H5D F;  4E9U A;  1VG7 A;  3WEG A;  3TFV A;  1UBY A;  3AQ0 A;  3QKC A;  1VG6 A;  5IVG A;  2E90 A;  3LLW A;  5ILZ A;  3ICM A;  4LFG A;  1V4E A;  3KRF B;  3N0G A;  5E8H A;  4H5E F;  5JV2 F;  1HXA A;  2FOR A;  2EWG A;  3P8R A;  3TS7 A;  2J1O A;  3NRI A;  2OA6 A;  1EZF A;  4H5C F;  1ZW5 A;  2O1O A;  3KBK A;  3WCC A;  4QPF A;  3PKO A;  3LZ9 A;  3SDU A;  2AEK A;  2I19 A;  5DHK A;  2ONG A;  5DZ2 A;  4LTZ A;  5AHU B;  1WL1 A;  5B03 A;  1HXG A;  3ICN A;  3LGZ B;  3ADZ A;  1YV5 A;  3KRA B;  3M01 A;  4NFJ F;  3ZMC A;  1UBV A;  2F92 F;  2FTZ A;  3KRA A;  3WCI A;  1KIY A;  2Q80 A;  3VJ8 A;  5AEL A;  3DYH A;  5ER8 A;  3DYG A;  5HN7 A;  2E8W A;  5IK9 A;  2F94 F;  5HN9 A;  3UCA A;  5EAT A;  2RAH A;  5JA0 F;  4KWD A;  3P5R A;  4EA1 A;  2F89 F;  1YYS A;  1WL0 A;  2P1C A;  3KB9 A;  3P8L A;  4LIX A;  3WCJ A;  4N1Z F;  1RQJ A;  2DH4 A;  5IMN A;  1WY0 A;  4GP1 A;  3LEE A;  4KVD A;  3EGT A;  4LLS A;  5ILH A;  1N1B A;  4NKE A;  1WL3 A;  1N21 A;  5B0J A;  4RXD A;  3MAV A;  4GAX A;  4DZW A;  4EA0 A;  2AET A;  3ICK A;  4OKZ A;  5DGN F;  3VJC A;  5ERM A;  1KIZ A;  1N23 A;  5DW7 A;  4WK5 A;  4QXS F;  5IL8 A;  1V4K A;  1VG3 A;  4EA2 A;  3WSB A;  5B00 A;  3NF2 A;  4DHD A;  2ZEU A;  3OYR A;  3WCH A;  3WE9 A;  5HN8 A;  3VJD A;  1V4I A;  4K10 A;  4LPG F;  5DGM F;  3SDT A;  1DGP A;  2AZJ A;  3ASX A;  3M9U A;  2F8Z F;  3BNY A;  5CG5 A;  3N0F A;  1N22 A;  4KVI A;  4E1E A;  3SDQ A;  3N3L F;  1YYU A;  2Z50 A;  4LLT A;  3LMD A;  3AQC B;  5ILJ A;  3W7F A;  4JYX A;  4DXJ A;  1UBX A;  2Z4W A;  3OAC A;  3WCA A;  2Q9Y A;  1JFG A;  2Z7H A;  4KVW A;  5HNA A;  5KSX F;  3LK5 A;  3OAB B;  4JZX A;  2PS6 A;  3KRF A;  1V4H A;  4LA5 A;  4F6V A;  2E8X A;  3TC1 A;  2F7M F;  5DGS F;  4FJQ A;  2Q9Z A;  3WEF A;  3CKE A;  2E8T A;  4NG6 A;  5B0L A;  3VJ9 A; 
#chains in the Genus database with same CATH homology
 5ERN A;  3PH7 A;  5IM1 A;  4F6X A;  1VG4 A;  1PS1 A;  4HD1 A;  2ZCR A;  5JV0 F;  2E94 A;  5IL3 A;  3P5P A;  4P0V A;  2ZCO A;  3KRP B;  4E9Z A;  4RXC A;  2ZCS A;  3Q30 A;  2Q58 A;  1YYR A;  5ILI A;  4LOB A;  5ERO A;  3S9V A;  3KRP A;  2OGD A;  5EAS A;  3VJE A;  1YHM A;  2ZEV A;  3LGK A;  4XQS F;  3VJB A;  5B0K A;  2PS7 A;  4KQ5 A;  3AQB B;  3N45 F;  2F8C F;  3N6K F;  5IMP A;  3B7L A;  3M02 A;  2QIS A;  3WCE A;  4KVY A;  3WEI A;  4JVJ F;  4ZQ8 A;  1YQ7 A;  2E95 A;  1N24 A;  3PDE A;  3QQV A;  1VG2 A;  4NKF A;  3WCM A;  4P0W A;  3MZV A;  1YHL A;  3KRC B;  2Z4X A;  3TFN A;  3V66 A;  4LZ0 A;  4FP4 A;  4KK2 A;  4P0X A;  3N5H F;  2J1P A;  3WEH A;  3ZCD A;  4OMG A;  5IN8 A;  5C05 A;  4RYP A;  4JZB A;  5I1U A;  3RYW A;  3KRO B;  2Z4Y A;  3N49 F;  3IBA A;  3N1W F;  3G4F A;  3SDR A;  1N1Z A;  4PVX F;  5DIQ F;  3KRO A;  3ACW A;  4NUA A;  1WMW A;  2ZY1 A;  2Z52 A;  4OGU A;  1YHK A;  2E8U A;  3BNX A;  5B02 A;  4KFA A;  3APZ A;  4LXW A;  3WJN A;  3SAE A;  1FPS A;  3LG5 A;  3TFP A;  2Z4Z A;  4GP2 A;  3RMG A;  3PYB A;  3G4D A;  2E8V A;  4N9U A;  2PS8 A;  2ONH A;  3ZL6 A;  3ICZ A;  4KQS A;  1HXC A;  3M00 A;  4DWB A;  3NPR A;  5A0I A;  3WCL A;  3WSA A;  4LPH F;  3WCG A;  2H8O A;  4LA6 A;  3OAB A;  3ZOU A;  4KPJ A;  3ZMB A;  3VJA A;  1WKZ A;  3RBM A;  3DYF A;  4OMH A;  3N1V F;  4LFE A;  1RQI A;  3WC9 A;  3SDV A;  4JXN A;  3S4J A;  5B0I A;  1YYQ A;  4KQU A;  4KKM A;  4NFK F;  1HM7 A;  1YYT A;  4XQR F;  5ILY A;  5EAU A;  3P41 A;  5B01 A;  3N46 F;  2Z4V A;  1UBW A;  1YJ4 A;  3WJK A;  4F62 A;  3IPI A;  4L2X F;  2PS5 A;  5E8K A;  2Z7I A;  3AE0 A;  5IK6 A;  2ZCQ A;  2E93 A;  4DI5 A;  4Q23 A;  5DJP F;  5AYP A;  5DJV F;  2AEL A;  5CG6 A;  1JFA A;  2AZK A;  2J5C A;  1RTR A;  4GA3 A;  3V1X A;  4MC3 A;  3Q1O A;  5B0M A;  2OPM A;  3ACX A;  4RXA A;  3WJO A;  3EFQ A;  3V1V A;  4MC0 A;  4XQT F;  4LTV A;  3M0G A;  4NFI F;  5JV1 F;  3WEK A;  2AZL A;  4LZC A;  3LSN A;  3LVS A;  3LJI A;  1WL2 A;  3WEJ A;  3KRC A;  5JUZ F;  4LUU A;  5DJR F;  3LOM A;  3N3D A;  5DHI A;  4DEM F;  3Q2Q A;  3NPK A;  5IKH A;  3RYE A;  2F9K F;  4JXY A;  5H9D A;  5IMI A;  5ILD A;  3N5J F;  3EZ3 A;  4KPD A;  2OPN A;  4UMJ A;  4KUX A;  5A0J A;  5AFX A;  5E8L A;  5A0K A;  3PYA A;  2E4O A;  3CP6 A;  1DI1 A;  3CC9 A;  4OKM A;  4LZ3 A;  2PS4 A;  1HM4 A;  5IK0 A;  1HX9 A;  3ID0 A;  5ILK A;  4MC8 A;  3WCB A;  4DWG A;  4PVY F;  5IKA A;  2E91 A;  2Z78 A;  1V4J A;  2E92 A;  3WCF A;  4RXE A;  2VF6 A;  3ACY A;  4RNQ A;  3WCD A;  4LFV F;  3LDW A;  3Q2Z A;  3OAC B;  1N20 A;  4H5D F;  4E9U A;  1VG7 A;  3WEG A;  3TFV A;  1UBY A;  3AQ0 A;  3QKC A;  1VG6 A;  5IVG A;  2E90 A;  3LLW A;  5ILZ A;  3ICM A;  4LFG A;  1V4E A;  3KRF B;  3N0G A;  5E8H A;  4H5E F;  5JV2 F;  1HXA A;  2FOR A;  2EWG A;  3P8R A;  3TS7 A;  2J1O A;  3NRI A;  2OA6 A;  1EZF A;  4H5C F;  1ZW5 A;  2O1O A;  3KBK A;  3WCC A;  4QPF A;  3PKO A;  3LZ9 A;  3SDU A;  2AEK A;  2I19 A;  5DHK A;  2ONG A;  5DZ2 A;  4LTZ A;  5AHU B;  1WL1 A;  5B03 A;  1HXG A;  3ICN A;  3LGZ B;  3ADZ A;  1YV5 A;  3KRA B;  3M01 A;  4NFJ F;  3ZMC A;  1UBV A;  2F92 F;  2FTZ A;  3KRA A;  3WCI A;  1KIY A;  2Q80 A;  3VJ8 A;  5AEL A;  3DYH A;  5ER8 A;  3DYG A;  5HN7 A;  2E8W A;  5IK9 A;  2F94 F;  5HN9 A;  3UCA A;  5EAT A;  2RAH A;  5JA0 F;  4KWD A;  3P5R A;  4EA1 A;  2F89 F;  1YYS A;  1WL0 A;  2P1C A;  3KB9 A;  3P8L A;  4LIX A;  3WCJ A;  4N1Z F;  1RQJ A;  2DH4 A;  5IMN A;  1WY0 A;  4GP1 A;  3LEE A;  4KVD A;  3EGT A;  4LLS A;  5ILH A;  1N1B A;  4NKE A;  1WL3 A;  1N21 A;  5B0J A;  4RXD A;  3MAV A;  4GAX A;  4DZW A;  4EA0 A;  2AET A;  3ICK A;  4OKZ A;  5DGN F;  3VJC A;  5ERM A;  1KIZ A;  1N23 A;  5DW7 A;  4WK5 A;  4QXS F;  5IL8 A;  1V4K A;  1VG3 A;  4EA2 A;  3WSB A;  5B00 A;  3NF2 A;  4DHD A;  2ZEU A;  3OYR A;  3WCH A;  3WE9 A;  5HN8 A;  3VJD A;  1V4I A;  4K10 A;  4LPG F;  5DGM F;  3SDT A;  1DGP A;  2AZJ A;  3ASX A;  3M9U A;  2F8Z F;  3BNY A;  5CG5 A;  3N0F A;  1N22 A;  4KVI A;  4E1E A;  3SDQ A;  3N3L F;  1YYU A;  2Z50 A;  4LLT A;  3LMD A;  3AQC B;  5ILJ A;  3W7F A;  4JYX A;  4DXJ A;  1UBX A;  2Z4W A;  3OAC A;  3WCA A;  2Q9Y A;  1JFG A;  2Z7H A;  4KVW A;  5HNA A;  5KSX F;  3LK5 A;  3OAB B;  4JZX A;  2PS6 A;  3KRF A;  1V4H A;  4LA5 A;  4F6V A;  2E8X A;  3TC1 A;  2F7M F;  5DGS F;  4FJQ A;  2Q9Z A;  3WEF A;  3CKE A;  2E8T A;  4NG6 A;  5B0L A;  3VJ9 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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