1ZY8K

The crystal structure of dihydrolipoamide dehydrogenase and dihydrolipoamide dehydrogenase-binding protein (didomain) subcomplex of human pyruvate dehydrogenase complex.
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
44
structure length
44
Chain Sequence
RLSPAARNILEKHSLDASQGTATGPRGIFTKEDALKLVQLKQTG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Oxidoreductase
molecule keywords Dihydrolipoyl dehydrogenase, mitochondrial
publication title How Dihydrolipoamide Dehydrogenase-binding Protein Binds Dihydrolipoamide Dehydrogenase in the Human Pyruvate Dehydrogenase Complex.
pubmed doi rcsb
source organism Homo sapiens
total genus 12
structure length 44
sequence length 44
chains with identical sequence L, M, N, O
ec nomenclature
pdb deposition date 2005-06-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
K PF00364 Biotin_lipoyl Biotin-requiring enzyme
K PF02817 E3_binding e3 binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.320.10 Few Secondary Structures Irregular Dihydrolipoamide Transferase E3-binding domain 1zy8K00
2F5ZK 1W4HA 1W4JA 1W3DA 1ZY8K 1W85I 3DVAI 2F60K 1W4FA 1BALA 1W4EA 2BTHA 1W88I 1W4IA 1EBDC 3DV0I 3RNME 2BTGA 2PDDA 1ZWVA 4QOYE 2WXCA 2EQ9C 1W4KA 2PDEA 1W4GA
chains in the Genus database with same CATH superfamily
2F5ZK 1W4HA 1W4JA 1W3DA 1ZY8K 1W85I 3DVAI 2F60K 1W4FA 1BALA 1W4EA 2BTHA 1W88I 1W4IA 1EBDC 3DV0I 3RNME 2BTGA 2PDDA 1ZWVA 4QOYE 2WXCA 2EQ9C 1W4KA 2PDEA 1W4GA
chains in the Genus database with same CATH topology
2F5ZK 1W4HA 1W4JA 1W3DA 1ZY8K 1W85I 3DVAI 2F60K 1W4FA 1BALA 1W4EA 2BTHA 1W88I 1W4IA 1EBDC 3DV0I 3RNME 2BTGA 2PDDA 1ZWVA 4QOYE 2WXCA 2EQ9C 1W4KA 2PDEA 1W4GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2F5Z K;  1W4H A;  1W4J A;  1W3D A;  1ZY8 K;  1W85 I;  3DVA I;  2F60 K;  1W4F A;  1BAL A;  1W4E A;  2BTH A;  1W88 I;  1W4I A;  1EBD C;  3DV0 I;  3RNM E;  2BTG A;  2PDD A;  1ZWV A;  4QOY E;  2WXC A;  2EQ9 C;  1W4K A;  2PDE A;  1W4G A; 
#chains in the Genus database with same CATH topology
 2F5Z K;  1W4H A;  1W4J A;  1W3D A;  1ZY8 K;  1W85 I;  3DVA I;  2F60 K;  1W4F A;  1BAL A;  1W4E A;  2BTH A;  1W88 I;  1W4I A;  1EBD C;  3DV0 I;  3RNM E;  2BTG A;  2PDD A;  1ZWV A;  4QOY E;  2WXC A;  2EQ9 C;  1W4K A;  2PDE A;  1W4G A; 
#chains in the Genus database with same CATH homology
 2F5Z K;  1W4H A;  1W4J A;  1W3D A;  1ZY8 K;  1W85 I;  3DVA I;  2F60 K;  1W4F A;  1BAL A;  1W4E A;  2BTH A;  1W88 I;  1W4I A;  1EBD C;  3DV0 I;  3RNM E;  2BTG A;  2PDD A;  1ZWV A;  4QOY E;  2WXC A;  2EQ9 C;  1W4K A;  2PDE A;  1W4G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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