2ERGA

Crystal structure of leu3 dna-binding domain with a single h50c mutation complexed with a 15mer dna duplex
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
65
structure length
65
Chain Sequence
FACVECRQQKSKCDACERAPEPCTKCAKKNVPCILKRDFRRTYKRARNEAIEKRFKELTRTLTNL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transcription activator/dna
molecule keywords 5'-D(*TP*TP*GP*CP*CP*GP*GP*TP*AP*CP*CP*GP*GP*CP*A)-3'
publication title Structure of a Leu3-DNA complex: recognition of everted CGG half-sites by a Zn2Cys6 binuclear cluster protein.
pubmed doi rcsb
source organism Saccharomyces cerevisiae
total genus 15
structure length 65
sequence length 65
chains with identical sequence B
ec nomenclature
pdb deposition date 2005-10-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00172 Zn_clus Fungal Zn(2)-Cys(6) binuclear cluster domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.240.10 Few Secondary Structures Irregular CD2-Gal4 Zn(2)-C6 fungal-type DNA-binding domain 2ergA00
2ER8A 1PYIA 1AW6A 2EREA 3ALCA 2HAPC 3COQA 1ZMEC 2ALCA 2ERGA 1F4SP 1F5EP 1D66A 1QP9A 1HWTC 1AJYA 1PYCA
chains in the Genus database with same CATH superfamily
2ER8A 1PYIA 1AW6A 2EREA 3ALCA 2HAPC 3COQA 1ZMEC 2ALCA 2ERGA 1F4SP 1F5EP 1D66A 1QP9A 1HWTC 1AJYA 1PYCA
chains in the Genus database with same CATH topology
2ER8A 1PYIA 1AW6A 2EREA 3ALCA 2HAPC 3COQA 1ZMEC 2ALCA 2ERGA 1F4SP 1F5EP 1D66A 1QP9A 1HWTC 1AJYA 1PYCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ER8 A;  1PYI A;  1AW6 A;  2ERE A;  3ALC A;  2HAP C;  3COQ A;  1ZME C;  2ALC A;  2ERG A;  1F4S P;  1F5E P;  1D66 A;  1QP9 A;  1HWT C;  1AJY A;  1PYC A; 
#chains in the Genus database with same CATH topology
 2ER8 A;  1PYI A;  1AW6 A;  2ERE A;  3ALC A;  2HAP C;  3COQ A;  1ZME C;  2ALC A;  2ERG A;  1F4S P;  1F5E P;  1D66 A;  1QP9 A;  1HWT C;  1AJY A;  1PYC A; 
#chains in the Genus database with same CATH homology
 2ER8 A;  1PYI A;  1AW6 A;  2ERE A;  3ALC A;  2HAP C;  3COQ A;  1ZME C;  2ALC A;  2ERG A;  1F4S P;  1F5E P;  1D66 A;  1QP9 A;  1HWT C;  1AJY A;  1PYC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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