2FK4A

Solution structure of the c-terminal zinc binding domain of the hpv16 e6 oncoprotein
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
67
structure length
67
Chain Sequence
AMSYSLYGTTLEQQYNKPLSDLLIRCINCQKPLSPEEKQRHLDKKQRFHNIRGRWTGRCMSCSRSSR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Metal binding protein, oncoprotein
molecule keywords Protein E6
publication title Structural and functional analysis of E6 oncoprotein: insights in the molecular pathways of human papillomavirus-mediated pathogenesis
pubmed doi rcsb
source organism Human papillomavirus type 16
total genus 10
structure length 67
sequence length 67
ec nomenclature
pdb deposition date 2006-01-04
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.240.40 Alpha Beta 2-Layer Sandwich CRO Repressor CRO Repressor 2fk4A00
2LJZA 4GIZC 2LJXA 4XR8F 2M3LA 2FK4A 2LJYA
chains in the Genus database with same CATH superfamily
2ORCA 4XR8F 2A63A 2ECSA 5CROA 2M3LA 1D1LA 4GIZC 1D1MA 2OVGA 3ORCA 1ORCA 6CROA 2CW1A 1WU7A 2LJYA 1COPD 2LJZA 2LJXA 3C6FA 2FK4A
chains in the Genus database with same CATH topology
2ORCA 4XR8F 2A63A 2ECSA 5CROA 2M3LA 1D1LA 4GIZC 1D1MA 2OVGA 3ORCA 1ORCA 6CROA 2CW1A 1WU7A 2LJYA 1COPD 2LJZA 2LJXA 2FK4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2LJZ A;  4GIZ C;  2LJX A;  4XR8 F;  2M3L A;  2FK4 A;  2LJY A; 
#chains in the Genus database with same CATH topology
 2ORC A;  4XR8 F;  2A63 A;  2ECS A;  5CRO A;  2M3L A;  1D1L A;  4GIZ C;  1D1M A;  2OVG A;  3ORC A;  1ORC A;  6CRO A;  2CW1 A;  1WU7 A;  2LJY A;  1COP D;  2LJZ A;  2LJX A;  3C6F A;  2FK4 A; 
#chains in the Genus database with same CATH homology
 2ORC A;  4XR8 F;  2A63 A;  2ECS A;  5CRO A;  2M3L A;  1D1L A;  4GIZ C;  1D1M A;  2OVG A;  3ORC A;  1ORC A;  6CRO A;  2CW1 A;  1WU7 A;  2LJY A;  1COP D;  2LJZ A;  2LJX A;  2FK4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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