2M3ZA

Nmr solution structure of hiv-1 nucleocapsid protein in complex with an inhibitor displaying a 2 inhibitors:1 nc stoichiometry
Total Genus 7
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
7
sequence length
55
structure length
55
Chain Sequence
IQKGNFRNQRKTVKCFNCGKEGHIAKNCRAPRKKGCWKCGKEGHQMKDCTERQAN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Viral protein
molecule keywords NUCLEOCAPSID PROTEIN P7
publication title Discovery and Structural Characterization of a New Inhibitor Series of HIV-1 Nucleocapsid Function: NMR Solution Structure Determination of a Ternary Complex Involving a 2:1 Inhibitor/NC Stoichiometry.
pubmed doi rcsb
source organism Human immunodeficiency virus type 1
total genus 7
structure length 55
sequence length 55
ec nomenclature ec 2.7.7.49: RNA-directed DNA polymerase.
pdb deposition date 2013-01-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00098 zf-CCHC Zinc knuckle
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.60.10 Few Secondary Structures Irregular HIV-1 Nucleocapsid Protein Zinc finger, CCHC-type 2m3zA00
1Q3YA 2L4LA 1U6PA 2LI8A 1F6UA 1WWEA 2M3ZA 1Q3ZA 2EC7A 3TS2A 1WWGA 2YSAA 1ESKA 1MFSA 1BJ6A 1WWDA 2EXFA 1WWFA 3TRZA 1A1TA 1AAFA 2IHXA 2CQFA 2JZWA 3NYBB 3TS0A 1A6BB
chains in the Genus database with same CATH superfamily
1Q3YA 2L4LA 1U6PA 2LI8A 1F6UA 1WWEA 2M3ZA 1Q3ZA 2EC7A 3TS2A 1WWGA 2YSAA 1ESKA 1MFSA 1BJ6A 1WWDA 2EXFA 1WWFA 3TRZA 1A1TA 1AAFA 2IHXA 2CQFA 2JZWA 3NYBB 3TS0A 1A6BB
chains in the Genus database with same CATH topology
1Q3YA 2L4LA 1U6PA 2LI8A 1F6UA 1WWEA 2M3ZA 1Q3ZA 2EC7A 3TS2A 1WWGA 2YSAA 1ESKA 1MFSA 1BJ6A 1WWDA 2EXFA 1WWFA 3TRZA 1A1TA 1AAFA 2IHXA 2CQFA 2JZWA 3NYBB 3TS0A 1A6BB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Q3Y A;  2L4L A;  1U6P A;  2LI8 A;  1F6U A;  1WWE A;  2M3Z A;  1Q3Z A;  2EC7 A;  3TS2 A;  1WWG A;  2YSA A;  1ESK A;  1MFS A;  1BJ6 A;  1WWD A;  2EXF A;  1WWF A;  3TRZ A;  1A1T A;  1AAF A;  2IHX A;  2CQF A;  2JZW A;  3NYB B;  3TS0 A;  1A6B B; 
#chains in the Genus database with same CATH topology
 1Q3Y A;  2L4L A;  1U6P A;  2LI8 A;  1F6U A;  1WWE A;  2M3Z A;  1Q3Z A;  2EC7 A;  3TS2 A;  1WWG A;  2YSA A;  1ESK A;  1MFS A;  1BJ6 A;  1WWD A;  2EXF A;  1WWF A;  3TRZ A;  1A1T A;  1AAF A;  2IHX A;  2CQF A;  2JZW A;  3NYB B;  3TS0 A;  1A6B B; 
#chains in the Genus database with same CATH homology
 1Q3Y A;  2L4L A;  1U6P A;  2LI8 A;  1F6U A;  1WWE A;  2M3Z A;  1Q3Z A;  2EC7 A;  3TS2 A;  1WWG A;  2YSA A;  1ESK A;  1MFS A;  1BJ6 A;  1WWD A;  2EXF A;  1WWF A;  3TRZ A;  1A1T A;  1AAF A;  2IHX A;  2CQF A;  2JZW A;  3NYB B;  3TS0 A;  1A6B B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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